J
Jan Mojzis
Researcher at University of Pavol Jozef Šafárik
Publications - 74
Citations - 1970
Jan Mojzis is an academic researcher from University of Pavol Jozef Šafárik. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 23, co-authored 63 publications receiving 1592 citations.
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Antiangiogenic effects of flavonoids and chalcones.
TL;DR: Flavonoids and chalcones regulate expression of VEGF, matrix metalloproteinases (MMPs), EGFR and inhibit NFkappaB, PI3-K/Akt, ERK1/2 signalling pathways, thereby causing strong antiangiogenic effects.
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Soy and breast cancer: focus on angiogenesis.
TL;DR: A review of the antiangiogenic properties of soy isoflavonoids examines their possible underlying mechanisms and concludes that genistein possesses pleiotropic molecular mechanisms of action.
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Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research.
Andrea Kapinová,Patrik Stefanicka,Peter Kubatka,Pavol Zubor,Sona Uramova,Martin Kello,Jan Mojzis,Dana Blahútová,Tawar Qaradakhi,Anthony Zulli,Martin Caprnda,Jan Danko,Zora Lasabova,Dietrich Büsselberg,Peter Kruzliak +14 more
TL;DR: The hypothesis that a mixture of wide range of phytochemicals with a plethora of biological activities present in whole plant-derived foods could have additive or synergistic effects against breast cancer is supported.
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Effects of static magnetic field on human leukemic cell line HL-60.
TL;DR: The metabolic activity retardation is observed in human leukemic cell line HL-60 exposed to 1-T SMF for 72 h and in the presence of the mixture of the antineoplastic drugs 5 fluorouracil, cisplatin, doxorubicin and vincristine.
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Flavonoids against the Warburg phenotype-concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism.
Marek Samec,Alena Liskova,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Constanze Buhrmann,Elizabeth Varghese,Mariam Abotaleb,Tawar Qaradakhi,Anthony Zulli,Martin Kello,Jan Mojzis,Pavol Zubor,Taeg Kyu Kwon,Mehdi Shakibaei,Dietrich Büsselberg,Gustavo R. Sarria,Olga Golubnitschaja,Peter Kubatka +18 more
TL;DR: Individualised profiling and patient stratification are presented as powerful tools for implementing targeted ‘anti-Warburg’ measures in the context of predictive, preventive and personalised medicine.