K
Kevin Zhai
Researcher at Qatar Foundation
Publications - 25
Citations - 542
Kevin Zhai is an academic researcher from Qatar Foundation. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 8, co-authored 18 publications receiving 160 citations. Previous affiliations of Kevin Zhai include Cornell University.
Papers
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Journal ArticleDOI
Flavonoids against the SARS-CoV-2 induced inflammatory storm.
Alena Liskova,Marek Samec,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Raghad Khalid Al-Ishaq,Mariam Abotaleb,Vladimir Nosal,Karol Kajo,Milad Ashrafizadeh,Ali Zarrabi,Aranka Brockmueller,Mehdi Shakibaei,Peter Sabaka,Ioana Mozos,David Ullrich,Robert Prosecky,Giampiero La Rocca,Martin Caprnda,Dietrich Büsselberg,Luis Rodrigo,Peter Kruzliak,Peter Kubatka +22 more
TL;DR: The potential role of flavonoids in the modulation of signaling pathways that are crucial for COVID-19 disease, particularly those related to inflammation and immunity, was discussed in this paper.
Journal ArticleDOI
Flavonoids against the Warburg phenotype-concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism.
Marek Samec,Alena Liskova,Lenka Koklesova,Samson Mathews Samuel,Kevin Zhai,Constanze Buhrmann,Elizabeth Varghese,Mariam Abotaleb,Tawar Qaradakhi,Anthony Zulli,Martin Kello,Jan Mojzis,Pavol Zubor,Taeg Kyu Kwon,Mehdi Shakibaei,Dietrich Büsselberg,Gustavo R. Sarria,Olga Golubnitschaja,Peter Kubatka +18 more
TL;DR: Individualised profiling and patient stratification are presented as powerful tools for implementing targeted ‘anti-Warburg’ measures in the context of predictive, preventive and personalised medicine.
Journal ArticleDOI
Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles.
Alena Liskova,Marek Samec,Lenka Koklesova,Aranka Brockmueller,Kevin Zhai,Basma Abdellatif,Manaal Siddiqui,Kamil Biringer,Erik Kudela,Martin Péč,Laura Kate Gadanec,Miroslava Šudomová,Sherif T. S. Hassan,Anthony Zulli,Mehdi Shakibaei,Frank A. Giordano,Dietrich Büsselberg,Olga Golubnitschaja,Peter Kubatka +18 more
TL;DR: In this paper, most recently updated data focused on the potent capacity of flavonoids to promote anti-cancer therapeutic effects and interprets all the collected research achievements in the frame-work of predictive, preventive, and personalized medicine.
Journal ArticleDOI
Calcium Entry through TRPV1: A Potential Target for the Regulation of Proliferation and Apoptosis in Cancerous and Healthy Cells.
TL;DR: The modulation of the TRPV1-enforced proliferation–apoptosis balance is a promising avenue in developing anti-cancer therapies and overcoming cancer drug resistance.
Journal ArticleDOI
Flavonoids Targeting HIF-1: Implications on Cancer Metabolism.
Marek Samec,Alena Liskova,Lenka Koklesova,Sandra Mersakova,Jan Strnadel,Karol Kajo,Martin Péč,Kevin Zhai,Karel Šmejkal,Sepideh Mirzaei,Kiavash Hushmandi,Milad Ashrafizadeh,Luciano Saso,Aranka Brockmueller,Mehdi Shakibaei,Dietrich Büsselberg,Peter Kubatka +16 more
TL;DR: In this article, the authors discuss the results of most recent studies evaluating the impact of flavonoids on HIF-1 accompanied by the regulation of critical enzymes contributing to the Warburg phenotype.