J
Janet E. Price
Researcher at University of Texas MD Anderson Cancer Center
Publications - 122
Citations - 8550
Janet E. Price is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Metastasis & Cancer. The author has an hindex of 48, co-authored 122 publications receiving 8221 citations. Previous affiliations of Janet E. Price include University of Texas at Austin & University of Texas Health Science Center at Houston.
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CCR7 and CXCR4 as Novel Biomarkers Predicting Axillary Lymph Node Metastasis in T1 Breast Cancer
Neslihan Cabioglu,M. Sertac Yazici,Banu Arun,Kristine Broglio,Gabriel N. Hortobagyi,Janet E. Price,Aysegul Sahin +6 more
TL;DR: The results suggest that the chemokine receptor CCR7 is a novel biomarker that can predict lymph node metastases in breast cancer and utilization of additional markers, such as CXCR4 and HER2-neu, further improves the prediction of the presence and extent of lymph node involvement.
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Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism
Yuhua Zhao,Hao Liu,Zixing Liu,Yan Ding,Susan P. LeDoux,Glenn L. Wilson,Richard Voellmy,Yifeng Lin,Wensheng Lin,Rita Nahta,Bolin Liu,Øystein Fodstad,Jieqing Chen,Yun Wu,Janet E. Price,Ming Tan +15 more
TL;DR: The findings show how glycolysis inhibition can dramatically enhance the therapeutic efficacy of trastuzumab in ErbB2-positive breast cancers, potentially useful as a strategy to overcome trastzumab resistance.
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Breast Cancer Metastasis: Challenges and Opportunities
Jing Lu,Patricia S. Steeg,Janet E. Price,Savitri Krishnamurthy,Sendurai A. Mani,James M. Reuben,Massimo Cristofanilli,Gabriela Dontu,Luc Bidaut,V. Valero,Gabriel N. Hortobagyi,Dihua Yu +11 more
TL;DR: Despite exciting progress in the understanding of breast cancer development and progression, and in the development of novel therapeutic strategies, breast cancer remains the second leading cause of cancer-related death in women.
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Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice.
TL;DR: Elevated VEGF expression contributes to the ability of breast cancer cells to form brain metastases, and targeting endothelial cells with a V EGF-receptor specific tyrosine kinase inhibitor reduced angiogenesis and restricted the growth of the brain metastase.
Journal Article
Differential permeability of the blood-brain barrier in experimental brain metastases produced by human neoplasms implanted into nude mice.
TL;DR: It is suggested that the permeability of the blood-brain barrier varies among different experimental brain metastases and that its function is related to the growth pattern and size of the lesions.