S
Savitri Krishnamurthy
Researcher at University of Texas MD Anderson Cancer Center
Publications - 296
Citations - 14094
Savitri Krishnamurthy is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 58, co-authored 251 publications receiving 11973 citations. Previous affiliations of Savitri Krishnamurthy include The Breast Cancer Research Foundation & University of Texas at Austin.
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Journal ArticleDOI
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
Serena Nik-Zainal,Serena Nik-Zainal,Helen Davies,Johan Staaf,Manasa Ramakrishna,Dominik Glodzik,Xueqing Zou,Inigo Martincorena,Ludmil B. Alexandrov,Sancha Martin,David C. Wedge,Peter Van Loo,Young Seok Ju,Michiel M. Smid,Arie B. Brinkman,Sandro Morganella,Miriam Ragle Aure,Ole Christian Lingjærde,Anita Langerød,Markus Ringnér,Sung-Min Ahn,Sandrine Boyault,Jane E. Brock,Annegien Broeks,Adam Butler,Christine Desmedt,Luc Dirix,Serge Dronov,Aquila Fatima,John A. Foekens,Moritz Gerstung,Gerrit Gk Hooijer,Se Jin Jang,David Jones,Hyung-Yong Kim,Tari Ta King,Savitri Krishnamurthy,Hee Jin Lee,Jeong-Yeon Lee,Yang Li,Stuart McLaren,Andrew Menzies,Ville Mustonen,Sarah O’Meara,Iris Pauporté,Xavier Pivot,Colin Ca Purdie,Keiran Raine,Kamna Ramakrishnan,Germán Fg Rodríguez-González,Gilles Romieu,Anieta M. Sieuwerts,Peter Pt Simpson,Rebecca Shepherd,Lucy Stebbings,Olafur Oa Stefansson,Jon W. Teague,Stefania Tommasi,Isabelle Treilleux,Gert Van den Eynden,Peter B. Vermeulen,Anne Vincent-Salomon,Lucy R. Yates,Carlos Caldas,Laura Van't Veer,Andrew Tutt,Andrew Tutt,Stian Knappskog,Benita Kiat Tee Bk Tan,Jos Jonkers,Åke Borg,Naoto T. Ueno,Christos Sotiriou,Alain Viari,P. Andrew Futreal,Peter J. Campbell,Paul N. Span,Steven Van Laere,Sunil R. Lakhani,Jorunn E. Eyfjord,Alastair M Thompson,Ewan Birney,Hendrik G. Stunnenberg,Marc J. van de Vijver,John W.M. Martens,Anne Lise Børresen-Dale,Andrea L. Richardson,Gu Kong,Gilles Thomas,Michael R. Stratton +89 more
TL;DR: This analysis of all classes of somatic mutation across exons, introns and intergenic regions highlights the repertoire of cancer genes and mutational processes operative, and progresses towards a comprehensive account of the somatic genetic basis of breast cancer.
Journal ArticleDOI
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics.
Bryan T. Hennessy,Ana M. Gonzalez-Angulo,Katherine Stemke-Hale,Michael Z. Gilcrease,Savitri Krishnamurthy,Ju Seog Lee,Jane Fridlyand,Aysegul A. Sahin,Roshan Agarwal,Corwin Joy,Wenbin Liu,David N. Stivers,Keith A. Baggerly,Mark S. Carey,Ana Lluch,Carlos Monteagudo,Xiaping He,Victor J. Weigman,Cheng Fan,Juan P. Palazzo,Gabriel N. Hortobagyi,Laura K. Nolden,Nicholas J. Wang,Vicente Valero,Joe W. Gray,Charles M. Perou,Gordon B. Mills +26 more
TL;DR: Metaplastic breast cancers (MBCs) are aggressive, chemoresistant tumors characterized by lineage plasticity as discussed by the authors, and they have unique DNA copy number aberrations compared with common breast cancers.
Journal ArticleDOI
Improved Axillary Evaluation Following Neoadjuvant Therapy for Patients With Node-Positive Breast Cancer Using Selective Evaluation of Clipped Nodes: Implementation of Targeted Axillary Dissection
Abigail S. Caudle,Wei T. Yang,Savitri Krishnamurthy,Elizabeth A. Mittendorf,Dalliah M. Black,Michael Z. Gilcrease,Isabelle Bedrosian,Brian P. Hobbs,Sarah M. DeSnyder,Rosa F. Hwang,Beatriz E. Adrada,Simona F. Shaitelman,Mariana Chavez-MacGregor,Benjamin Smith,Rosalind P. Candelaria,Gildy Babiera,Basak E. Dogan,Lumarie Santiago,Kelly K. Hunt,Henry Mark Kuerer +19 more
TL;DR: Marking nodes with biopsy-confirmed metastatic disease allows for selective removal and improves pathologic evaluation for residual nodal disease after chemotherapy, as determined in patients undergoing complete axillary lymphadenectomy.
Journal ArticleDOI
Circulating tumour cells in non-metastatic breast cancer: a prospective study
Anthony Lucci,Carolyn S. Hall,A. Lodhi,A. Bhattacharyya,A. Anderson,Lianchun Xiao,Isabelle Bedrosian,Henry Mark Kuerer,Savitri Krishnamurthy +8 more
TL;DR: The presence of one or more circulating tumour cells predicted early recurrence and decreased overall survival in chemonaive patients with non-metastatic breast cancer and results suggest that assessment of circulating tumours might provide important prognostic information in these patients.
Journal ArticleDOI
Inflammatory Breast Cancer: The Disease, the Biology, the Treatment
Fredika M. Robertson,Melissa L. Bondy,Wei Yang,Hideko Yamauchi,Shannon N. Wiggins,Samira A. Kamrudin,Savitri Krishnamurthy,Huong T. Le-Petross,Luc Bidaut,Audrey N. Player,Sanford H. Barsky,Wendy A. Woodward,Thomas A. Buchholz,Anthony Lucci,Naoto T. Ueno,Massimo Cristofanilli +15 more
TL;DR: In this paper, a review examines IBC's unique clinical presentation, pathology, epidemiology, imaging, and biology and details current multidisciplinary management of the disease, which comprises systemic therapy, surgery, and radiation therapy.