J
Janet K. Jansson
Researcher at Pacific Northwest National Laboratory
Publications - 285
Citations - 56152
Janet K. Jansson is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 79, co-authored 269 publications receiving 46101 citations. Previous affiliations of Janet K. Jansson include United States Department of Energy & Swedish University of Agricultural Sciences.
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Metagenomics, metatranscriptomics and single cell genomics reveal functional response of active Oceanospirillales to Gulf oil spill
Olivia U. Mason,Terry C. Hazen,Sharon Borglin,Patrick S. G. Chain,Eric A. Dubinsky,Julian L. Fortney,James Han,Hoi-Ying N. Holman,Jenni Hultman,Regina Lamendella,Rachel Mackelprang,Stephanie Malfatti,Lauren M. Tom,Susannah G. Tringe,Tanja Woyke,Jizhong Zhou,Edward M. Rubin,Janet K. Jansson +17 more
Abstract: The Deepwater Horizon oil spill in the Gulf of Mexico resulted in a deep-sea hydrocarbon plume that caused a shift in the indigenous microbial community composition with unknown ecological consequences. Early in the spill history, a bloom of uncultured, thus uncharacterized, members of the Oceanospirillales was previously detected, but their role in oil disposition was unknown. Here our aim was to determine the functional role of the Oceanospirillales and other active members of the indigenous microbial community using deep sequencing of community DNA and RNA, as well as single-cell genomics. Shotgun metagenomic and metatranscriptomic sequencing revealed that genes for motility, chemotaxis and aliphatic hydrocarbon degradation were significantly enriched and expressed in the hydrocarbon plume samples compared with uncontaminated seawater collected from plume depth. In contrast, although genes coding for degradation of more recalcitrant compounds, such as benzene, toluene, ethylbenzene, total xylenes and polycyclic aromatic hydrocarbons, were identified in the metagenomes, they were expressed at low levels, or not at all based on analysis of the metatranscriptomes. Isolation and sequencing of two Oceanospirillales single cells revealed that both cells possessed genes coding for n-alkane and cycloalkane degradation. Specifically, the near-complete pathway for cyclohexane oxidation in the Oceanospirillales single cells was elucidated and supported by both metagenome and metatranscriptome data. The draft genome also included genes for chemotaxis, motility and nutrient acquisition strategies that were also identified in the metagenomes and metatranscriptomes. These data point towards a rapid response of members of the Oceanospirillales to aliphatic hydrocarbons in the deep sea.
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Correction to: Genetic and metabolic links between the murine microbiome and memory.
Jian-Hua Mao,Young-Mo Kim,Yan-Xia Zhou,Yan-Xia Zhou,Dehong Hu,Chenhan Zhong,Hang Chang,Colin J. Brislawn,Sarah J. Fansler,Sasha A. Langley,Yunshan Wang,Yunshan Wang,B. Y. Loulou Peisl,Susan E. Celniker,David W. Threadgill,Paul Wilmes,Galya Orr,Thomas O. Metz,Janet K. Jansson,Antoine M. Snijders +19 more
TL;DR: An amendment to this paper has been published and can be accessed via the original article.
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Erratum: Tackling soil diversity with the assembly of large, complex metagenomes (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 13, (4904-4909) doi:10.1073/pnas.1402564111)
Adina Howe,Janet K. Jansson,Stephanie Malfatti,Susannah G. Tringe,James M. Tiedje,Charles R. Brown +5 more
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Metagenomic analysis of microbial communities across a transect from low to highly hydrocarbon-contaminated soils in King George Island, Maritime Antarctica
Diogo Jurelevicius,Raphael da Silva Pereira,Fabio Faria da Mota,Juliano C. Cury,Ivan Cardoso de Oliveira,Alexandre S. Rosado,Alexandre S. Rosado,Olivia U. Mason,Janet K. Jansson,Lucy Seldin +9 more
TL;DR: In this article, the authors gratefully acknowledge the Earth Microbiome Program (EMP) for the sequencing data presented in this study, which was supported by grants from Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES, financial code 001), and Fundacao De Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ).