R
Regina Lamendella
Researcher at Juniata College
Publications - 98
Citations - 6095
Regina Lamendella is an academic researcher from Juniata College. The author has contributed to research in topics: Medicine & Microbiome. The author has an hindex of 28, co-authored 83 publications receiving 5014 citations. Previous affiliations of Regina Lamendella include Ohio State University & University of Cincinnati.
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Journal ArticleDOI
Deep-sea oil plume enriches indigenous oil-degrading bacteria.
Terry C. Hazen,Eric A. Dubinsky,Todd Z. DeSantis,Gary L. Andersen,Yvette M. Piceno,Navjeet Singh,Janet K. Jansson,Alexander J. Probst,Sharon Borglin,Julian L. Fortney,William T. Stringfellow,William T. Stringfellow,Markus Bill,Mark E. Conrad,Lauren M. Tom,Krystle L. Chavarria,Thana R. Alusi,Regina Lamendella,Dominique C. Joyner,Chelsea Spier,Jacob Bælum,Manfred Auer,Marcin Zemla,Romy Chakraborty,Eric Sonnenthal,Patrik D'haeseleer,Hoi-Ying N. Holman,Shariff Osman,Zhenmei Lu,Joy D. Van Nostrand,Ye Deng,Jizhong Zhou,Jizhong Zhou,Olivia U. Mason +33 more
TL;DR: It is reported that the dispersed hydrocarbon plume stimulated deep-sea indigenous γ-Proteobacteria that are closely related to known petroleum degraders, and the potential exists for intrinsic bioremediation of the oil plume in the deep-water column without substantial oxygen drawdown.
Journal ArticleDOI
Dynamics of the human gut microbiome in inflammatory bowel disease.
Jonas Halfvarson,Colin J. Brislawn,Regina Lamendella,Yoshiki Vázquez-Baeza,William A. Walters,Lisa M. Bramer,Mauro D'Amato,Mauro D'Amato,Ferdinando Bonfiglio,Daniel McDonald,Antonio Gonzalez,Erin E. McClure,Mitchell F. Dunklebarger,Rob Knight,Janet K. Jansson +14 more
TL;DR: There was some correlation between observed dramatic fluctuations in the gut microbiome and intensified medication due to a flare of the disease, and these results will help guide therapies that will redirect the Gut microbiome towards a healthy state and maintain remission in IBD.
Journal ArticleDOI
Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill
Olivia U. Mason,Olivia U. Mason,Terry C. Hazen,Terry C. Hazen,Sharon Borglin,Patrick S. G. Chain,Patrick S. G. Chain,Eric A. Dubinsky,Julian L. Fortney,James Han,James Han,Hoi-Ying N. Holman,Jenni Hultman,Regina Lamendella,Rachel Mackelprang,Stephanie Malfatti,Stephanie Malfatti,Lauren M. Tom,Susannah G. Tringe,Tanja Woyke,Jizhong Zhou,Jizhong Zhou,Edward M. Rubin,Janet K. Jansson,Janet K. Jansson +24 more
TL;DR: The draft genome included genes for chemotaxis, motility and nutrient acquisition strategies that were also identified in the metagenomes and metatranscriptomes, which point towards a rapid response of members of the Oceanospirillales to aliphatic hydrocarbons in the deep sea.
Journal ArticleDOI
Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease
Alison R. Erickson,Brandi L. Cantarel,Regina Lamendella,Youssef Darzi,Emmanuel F. Mongodin,Chongle Pan,Manesh Shah,Jonas Halfvarson,Curt Tysk,Bernard Henrissat,Jeroen Raes,Nathan C Verberkmoes,Claire M. Fraser,Robert L. Hettich,Janet K. Jansson +14 more
TL;DR: The eco-systems biology approach underscores the link between the gut microbiota and functional alterations in the pathophysiology of Crohn's disease and aids in identification of novel diagnostic targets and disease specific biomarkers.
Journal ArticleDOI
Comparative fecal metagenomics unveils unique functional capacity of the swine gut.
Regina Lamendella,Regina Lamendella,Jorge W. Santo Domingo,Shreya Ghosh,John Martinson,Daniel B. Oerther,Daniel B. Oerther +6 more
TL;DR: The results from this metagenomic survey demonstrated the presence of genes associated with resistance to antibiotics and carbohydrate metabolism suggesting that the swine gut microbiome may be shaped by husbandry practices.