J
Jason E. Long
Researcher at Genentech
Publications - 42
Citations - 4242
Jason E. Long is an academic researcher from Genentech. The author has contributed to research in topics: Interneuron & Ganglionic eminence. The author has an hindex of 27, co-authored 37 publications receiving 3897 citations. Previous affiliations of Jason E. Long include University of California, San Francisco.
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Journal ArticleDOI
The endocannabinoid system controls key epileptogenic circuits in the hippocampus.
Krisztina Monory,Federico Massa,Federico Massa,Michaela Egertová,Matthias Eder,Heike Blaudzun,Ruth E. Westenbroek,Wolfgang Kelsch,Wolfgang Jacob,Rudolf Marsch,Marc Ekker,Jason E. Long,John L.R. Rubenstein,Sandra Goebbels,Klaus-Armin Nave,Matthew J. During,Matthias Klugmann,Barbara Wölfel,Hans-Ulrich Dodt,Walter Zieglgänsberger,Carsten T. Wotjak,Ken Mackie,Maurice R. Elphick,Giovanni Marsicano,Giovanni Marsicano,Beat Lutz +25 more
TL;DR: The direct endocannabinoid-mediated control of hippocampal glutamatergic neurotransmission may constitute a promising therapeutic target for the treatment of disorders associated with excessive excitatory neuronal activity.
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Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.
Nuria Flames,Jason E. Long,Alistair N. Garratt,Tobias M. Fischer,Martin Gassmann,Carmen Birchmeier,Cary Lai,John L.R. Rubenstein,Oscar Marín +8 more
TL;DR: Observations provide evidence that Neuregulin-1 and its ErbB4 receptor directly control neuronal migration in the nervous system.
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CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration
Yanling Wang,Guangnan Li,Amelia Stanco,Jason E. Long,Dianna Crawford,Gregory B. Potter,Samuel J. Pleasure,Timothy W. Behrens,John L.R. Rubenstein +8 more
TL;DR: It is suggested that CXCR4 and CX CR7 have distinct roles and signal transduction in regulating interneuron movement and laminar positioning.
Journal ArticleDOI
A subpopulation of olfactory bulb GABAergic interneurons is derived from Emx1- and Dlx5/6-expressing progenitors.
Minoree Kohwi,Magdalena A. Petryniak,Jason E. Long,Marc Ekker,Kunihiko Obata,Yuchio Yanagawa,John L.R. Rubenstein,Arturo Alvarez-Buylla +7 more
TL;DR: The results suggest that some OB interneurons are derived from progenitors outside the LGE and that precursors expressing what has classically been considered a pallial transcription factor generate GABAergic interneeurons.
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Distinct Molecular Pathways for Development of Telencephalic Interneuron Subtypes Revealed Through Analysis of Lhx6 Mutants
Yangu Zhao,Pierre Flandin,Jason E. Long,Melissa Dela Cuesta,Heiner Westphal,John L.R. Rubenstein +5 more
TL;DR: Evidence is provided that Lhx6 mediates these effects through promoting expression of receptors that regulate interneuron migration, and through promoting the expression of transcription factors either known (Arx) or implicated (bMaf, Cux2, and NPAS1) in controllingInterneuron development.