J
Jean-Christophe Leroux
Researcher at ETH Zurich
Publications - 320
Citations - 24325
Jean-Christophe Leroux is an academic researcher from ETH Zurich. The author has contributed to research in topics: Micelle & Drug carrier. The author has an hindex of 74, co-authored 307 publications receiving 21898 citations. Previous affiliations of Jean-Christophe Leroux include Delaware Biotechnology Institute & McGill University.
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Journal ArticleDOI
Hydrophilic Nanoreservoirs Embedded into Polymeric Micro/Nanoparticles: An Approach To Compatibilize Polar Molecules with Hydrophobic Matrixes
Hui Gao,Marie-Christine Jones,Jian Chen,Yongri Liang,Robert E. Prud'homme,Jean-Christophe Leroux +5 more
TL;DR: In this article, reverse polymeric micelles obtained from the self-assembly of partially alkylated star-shaped poly(glycerol methacrylate)s were embedded into poly(ester) micro/nanospheres to encapsulate polar gues...
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Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions
Giovanna Giacalone,Simon Matoori,Valentina Agostoni,Vincent Forster,Meriam Kabbaj,Sarah Eggenschwiler,Martin Lussi,Andrea De Gottardi,Nicola Zamboni,Jean-Christophe Leroux +9 more
TL;DR: Findings confirm that LSPD is a potentially safe and effective approach for treating hyperammonemic crises in the context of acute‐on‐chronic liver failure.
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Investigational Therapies for Primary Hyperoxaluria.
TL;DR: Current advances in the development of supportive measures for primary hyperoxaluria are presented and discussed and include the administration of probiotics favouring the intestinal secretion of excess oxalate.
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Bio‐reduction of Redox‐Sensitive Albumin Conjugates in FcRn‐Expressing Cells
Lorine Brülisauer,Gina Valentino,Sakura Morinaga,Kübra Cam,Jens T. Bukrinski,Marc A. Gauthier,Jean-Christophe Leroux +6 more
TL;DR: A detailed bio-reduction analysis of redox-sensitive albumin conjugates in two FcRn-expressing cell lines has been performed and indicates that the Fc Rn-mediated recycling pathway is not (or is only poorly) bio- Redox-reducing.
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The effect of settling on cytotoxicity evaluation of SiO2 nanoparticles
Anastasia Spyrogianni,Georgios A. Sotiriou,Georgios A. Sotiriou,Davide Brambilla,Jean-Christophe Leroux,Sotiris E. Pratsinis +5 more
TL;DR: In this article, the authors evaluate quantitatively the importance of nanoparticle settling for the in vitro cytotoxicity evaluation of aerosol-made, fractal-like SiO 2 nanoparticles that have similar agglomerate size and structure but varying primary particle diameter.