J
Jean-Paul Guthmann
Researcher at Institut de veille sanitaire
Publications - 80
Citations - 3567
Jean-Paul Guthmann is an academic researcher from Institut de veille sanitaire. The author has contributed to research in topics: Population & Malaria. The author has an hindex of 32, co-authored 77 publications receiving 3315 citations.
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Journal ArticleDOI
Relapses of Plasmodium vivax Infection Usually Result from Activation of Heterologous Hypnozoites
Mallika Imwong,Georges Snounou,Sasithon Pukrittayakamee,Naowarat Tanomsing,Jung Ryong Kim,Jung Ryong Kim,Amitab Nandy,Jean-Paul Guthmann,François Nosten,François Nosten,Jane M. Carlton,Sornchai Looareesuwan,Shalini Nair,Daniel Sudimack,Nicholas P. J. Day,Nicholas P. J. Day,Tim J. Anderson,Nicholas J. White,Nicholas J. White +18 more
TL;DR: In this article, combined genetic data from two genotyping approaches showed that novel P. vivax populations were present in the majority of patients with recurrent infection (107 [72%] of 149 patients overall [78% of patients in Thailand, 75% of patient in Myanmar {Burma}, and 63% of disease patients in India]).
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A large outbreak of hepatitis E among a displaced population in Darfur, Sudan, 2004: the role of water treatment methods.
Jean-Paul Guthmann,Hilde Kløvstad,Delia Boccia,Nuha Hamid,Loretxu Pinoges,Jacques-Yves Nizou,Mercedes Tatay,Francisco Diaz,Alain Moren,Rebecca F. Grais,Iza Ciglenecki,Elisabeth Nicand,Philippe J Guerin +12 more
TL;DR: Current recommendations to ensure a safe water supply may have been insufficient to inactivate HEV and control this epidemic in Darfur, which highlights the need to evaluate current water treatment methods and to identify alternative solutions adapted to complex emergencies.
Journal ArticleDOI
High Mortality Associated with an Outbreak of Hepatitis E among Displaced Persons in Darfur, Sudan
Delia Boccia,Jean-Paul Guthmann,Hilde Kløvstad,Nuha Hamid,Mercedes Tatay,Iza Ciglenecki,Jacques-Yves Nizou,Elisabeth Nicand,Philippe J Guerin +8 more
TL;DR: This large epidemic of HEV infection illustrates the dramatic impact of this disease on pregnant women and timely interventions and a vaccine are urgently needed to prevent mortality in this special group of women.
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Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria
Richard Pearce,Hirva Pota,Marie-Solange Evehe,El-Hadj Bâ,Ghyslain Mombo-Ngoma,Ghyslain Mombo-Ngoma,Allen L Malisa,Rosalynn Ord,Walter O. Inojosa,Alexandre Matondo,Diadier Diallo,Wilfred Fon Mbacham,Ingrid van den Broek,Todd D. Swarthout,Asefaw Getachew,Seyoum Dejene,Martin P. Grobusch,Martin P. Grobusch,Fanta Njie,Samuel Dunyo,Margaret Kweku,Seth Owusu-Agyei,Daniel Chandramohan,Maryline Bonnet,Jean-Paul Guthmann,Sian E. Clarke,Karen I. Barnes,Elizabeth Streat,Stark Katokele,Petrina Uusiku,Chris O. Agboghoroma,Olufunmilayo Y. Elegba,Badara Cisse,Ishraga E. A-Elbasit,Hayder A. Giha,Hayder A. Giha,S. Patrick Kachur,Caroline A. Lynch,John B. Rwakimari,Pascalina Chanda,Moonga Hawela,Brian L. Sharp,Inbarani Naidoo,Cally Roper +43 more
TL;DR: Cally Roper and colleagues analyze the distribution of sulfadoxine resistance mutations and flanking microsatellite loci to trace the emergence and dispersal of drug-resistant Plasmodium falciparum malaria in Africa.
Journal ArticleDOI
In vivo parasitological measures of artemisinin susceptibility.
Kasia Stepniewska,Kasia Stepniewska,Elizabeth A. Ashley,Elizabeth A. Ashley,Sue J. Lee,Sue J. Lee,Nicholas M. Anstey,Karen I. Barnes,Tran Quang Binh,Umberto D'Alessandro,Nicholas P. J. Day,Nicholas P. J. Day,Peter J. de Vries,Grant Dorsey,Jean-Paul Guthmann,Mayfong Mayxay,Paul N. Newton,Piero Olliaro,Piero Olliaro,Lyda Osorio,Ric N. Price,Mark Rowland,Frank Smithuis,Walter R. J. Taylor,François Nosten,François Nosten,Nicholas J. White,Nicholas J. White +27 more
TL;DR: In this article, the authors analyzed data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low, moderate and high levels of malaria transmission across the world and identified a simple in vivo screening measure for Artemisinin resistance.