F
Frank Smithuis
Researcher at University of Oxford
Publications - 98
Citations - 4441
Frank Smithuis is an academic researcher from University of Oxford. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 30, co-authored 85 publications receiving 3637 citations. Previous affiliations of Frank Smithuis include Médecins Sans Frontières & Mahidol University.
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Journal ArticleDOI
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
Kyaw Myo Tun,Mallika Imwong,Khin Maung Lwin,Aye A. Win,Tin Maung Hlaing,Thaung Hlaing,Khin Lin,Myat Phone Kyaw,Katherine Plewes,Katherine Plewes,M. Abul Faiz,Mehul Dhorda,Phaik Yeong Cheah,Phaik Yeong Cheah,Sasithon Pukrittayakamee,Elizabeth A. Ashley,Elizabeth A. Ashley,Tim J. Anderson,Shalini Nair,Marina McDew-White,Jennifer A. Flegg,Eric P. M. Grist,Philippe Allard Guérin,Richard J. Maude,Richard J. Maude,Frank Smithuis,Arjen M. Dondorp,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas P. J. Day,François Nosten,Nicholas J. White,Nicholas J. White,Charles J. Woodrow,Charles J. Woodrow +34 more
TL;DR: Assessment of the spread of artemisinin-resistant P falciparum in Myanmar finds Artemisinin resistance extends across much of Myanmar, and Appropriate therapeutic regimens should be tested urgently and implemented comprehensively if spread of warfarin resistance to other regions is to be avoided.
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The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study
Mallika Imwong,Kanokon Suwannasin,Chanon Kunasol,Kreepol Sutawong,Mayfong Mayxay,Mayfong Mayxay,Huy Rekol,Frank Smithuis,Tin Maung Hlaing,Kyaw Myo Tun,Rob W. van der Pluijm,Rob W. van der Pluijm,Rupam Tripura,Olivo Miotto,Olivo Miotto,Didier Menard,Mehul Dhorda,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,Arjen M. Dondorp,Arjen M. Dondorp +22 more
TL;DR: The results suggest that the dominant artemisinin-resistant P falciparum C580Y lineage probably arose in western Cambodia and then spread to Thailand and Laos, outcompeting other parasites and acquiring piperaquine resistance.
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A Selective Sweep Driven by Pyrimethamine Treatment in Southeast Asian Malaria Parasites
Shalini Nair,Jeff T. Williams,Alan Brockman,Lucy Paiphun,Mayfong Mayxay,Paul N. Newton,Jean Paul Guthmann,Frank Smithuis,Tran Tinh Hien,Nicholas J. White,François Nosten,Tim J. Anderson +11 more
TL;DR: Scanning the malaria parasite genome for evidence of recent selection may prove an extremely effective way to locate genes underlying recently evolved traits such as drug resistance, as well as providing an opportunity to study the dynamics of selective events that have occurred recently or are currently in progress.
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Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross‐sectional survey on the prevalence of fake antimalarials
Arjen M. Dondorp,Paul N. Newton,Paul N. Newton,Mayfong Mayxay,W. Van Damme,Frank Smithuis,Shunmay Yeung,Shunmay Yeung,A. Petit,Antony J. Lynam,Arlyne Johnson,Tran Tinh Hien,Rose McGready,Jj J. Farrar,Jj J. Farrar,Sornchai Looareesuwan,N P Day,N P Day,Michael D. Green,Nicholas J. White,Nicholas J. White +20 more
TL;DR: This study aims to assess the prevalence of counterfeit antimalarial drugs in Southeast (SE) Asia and to establish a database of known and suspected counterfeit drugs in the region.
Journal ArticleDOI
Fake artesunate in southeast Asia
Paul N. Newton,Paul N. Newton,Stephane Proux,Stephane Proux,Michael D. Green,Frank Smithuis,Jan Rozendaal,Sompol Prakongpan,Kesinee Chotivanich,Mayfong Mayxay,Sornchai Looareesuwan,Jeremy Farrar,François Nosten,Nicholas J. White,Nicholas J. White +14 more
TL;DR: The validated, simple, and inexpensive Fast Red TR dye technique will assist national malaria control authorities in urgently needed campaigns to stop this murderous trade.