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Angélique Robin
Researcher at Institut Gustave Roussy
Publications - 11
Citations - 762
Angélique Robin is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Lung cancer & Cisplatin. The author has an hindex of 9, co-authored 11 publications receiving 683 citations. Previous affiliations of Angélique Robin include French Institute of Health and Medical Research & University of Paris-Sud.
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Journal ArticleDOI
ERCC1 Isoform Expression and DNA Repair in Non-Small-Cell Lung Cancer
Luc Friboulet,Ken A. Olaussen,Ken A. Olaussen,Jean Pierre Pignon,Frances A. Shepherd,Ming-Sound Tsao,Stephen L. Graziano,Robert A. Kratzke,Jean-Yves Douillard,Lesley Seymour,Robert Pirker,Martin Filipits,Fabrice Andre,Fabrice Andre,Eric Solary,Eric Solary,Florence Ponsonnailles,Florence Ponsonnailles,Angélique Robin,Angélique Robin,Annabelle Stoclin,Annabelle Stoclin,Nicolas Dorvault,Nicolas Dorvault,Frédéric Commo,Frédéric Commo,Julien Adam,Julien Adam,Elsa Vanhecke,Elsa Vanhecke,Patrick Saulnier,Jürgen Thomale,Thierry Le Chevalier,Thierry Le Chevalier,Ariane Dunant,Vanessa Rousseau,Gwénaël Le Teuff,Elisabeth Brambilla,Jean-Charles Soria,Jean-Charles Soria +39 more
TL;DR: It was found that none of the 16 antibodies could distinguish among the four ERCC1 protein isoforms, whereas only one isoform produced a protein that had full capacities for nucleotide excision repair and cisplatin resistance.
Journal ArticleDOI
Cisplatin resistance associated with PARP hyperactivation.
Judith Michels,Ilio Vitale,Lorenzo Galluzzi,Julien Adam,Ken A. Olaussen,Oliver Kepp,Laura Senovilla,Ibtissam Talhaoui,Justine Guegan,David Enot,Monique Talbot,Angélique Robin,Philippe Girard,Cedric Orear,Delphine Lissa,Abdul Qader Sukkurwala,Pauline Garcia,Parviz Behnam-Motlagh,Kimitoshi Kohno,Gen Sheng Wu,Catherine Brenner,Philippe Dessen,Murat Saparbaev,Jean-Charles Soria,Maria Castedo,Guido Kroemer +25 more
TL;DR: It is shown that PARP1 is highly expressed and constitutively hyperactivated in a majority of human CDDP-resistant cancer cells of distinct histologic origin, becoming susceptible to PARP inhibitor-induced apoptosis.
Journal ArticleDOI
Prognostic impact of vitamin B6 metabolism in lung cancer.
Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,Ilio Vitale,Ilio Vitale,Ilio Vitale,Laura Senovilla,Laura Senovilla,Laura Senovilla,Ken A. Olaussen,Ken A. Olaussen,Ken A. Olaussen,Guillaume Pinna,Guillaume Pinna,Tobias Eisenberg,Aicha Goubar,Aicha Goubar,Aicha Goubar,Isabelle Martins,Isabelle Martins,Isabelle Martins,Judith Michels,Judith Michels,Judith Michels,Gueorgui Kratassiouk,Gueorgui Kratassiouk,Didac Carmona-Gutierrez,Marie Scoazec,Erika Vacchelli,Erika Vacchelli,Erika Vacchelli,Frédéric Schlemmer,Frédéric Schlemmer,Frédéric Schlemmer,Oliver Kepp,Oliver Kepp,Oliver Kepp,Shensi Shen,Shensi Shen,Shensi Shen,Maximilien Tailler,Maximilien Tailler,Maximilien Tailler,Mireia Niso-Santano,Mireia Niso-Santano,Mireia Niso-Santano,Eugenia Morselli,Eugenia Morselli,Eugenia Morselli,Alfredo Criollo,Alfredo Criollo,Alfredo Criollo,Sandy Adjemian,Sandy Adjemian,Sandy Adjemian,Mohamed Jemaà,Mohamed Jemaà,Mohamed Jemaà,Kariman Chaba,Kariman Chaba,Claire Pailleret,Claire Pailleret,Claire Pailleret,Mickaël Michaud,Mickaël Michaud,Mickaël Michaud,Federico Pietrocola,Federico Pietrocola,Federico Pietrocola,Nicolas Tajeddine,Nicolas Tajeddine,Nicolas Tajeddine,Thibault De La Motte Rouge,Natalia Araujo,Natalia Araujo,Nadya Morozova,Nadya Morozova,Thomas Robert,Hugues Ripoche,Hugues Ripoche,Frédéric Commo,Frédéric Commo,Frédéric Commo,Benjamin Besse,Pierre Validire,Pierre Fouret,Pierre Fouret,Angélique Robin,Angélique Robin,Angélique Robin,Nicolas Dorvault,Nicolas Dorvault,Nicolas Dorvault,Philippe Girard,Sebastien Gouy,Patricia Pautier,Nora Jägemann,Ann Christin Nickel,Sabrina Marsili,Caroline Paccard,Caroline Paccard,Caroline Paccard,Nicolas Servant,Nicolas Servant,Nicolas Servant,Philippe Hupé,Carmen Behrens,Parviz Behnam-Motlagh,Kimitoshi Kohno,Isabelle Cremer,Diane Damotte,Marco Alifano,Øivind Midttun,Per Magne Ueland,Vladimir Lazar,Philippe Dessen,Philippe Dessen,Hans Zischka,Etienne Chatelut,Maria Castedo,Maria Castedo,Maria Castedo,Frank Madeo,Emmanuel Barillot,Emmanuel Barillot,Emmanuel Barillot,Juergen Thomale,Ignacio I. Wistuba,Catherine Sautès-Fridman,Catherine Sautès-Fridman,Laurence Zitvogel,Laurence Zitvogel,Jean-Charles Soria,Annick Harel-Bellan,Annick Harel-Bellan,Guido Kroemer +135 more
TL;DR: Results indicate that PDXK expression levels constitute a biomarker for risk stratification among patients with NSCLC, in line with a general role of vitamin B6 in stress responses.
Journal ArticleDOI
TPF induction chemotherapy increases PD-L1 expression in tumour cells and immune cells in head and neck squamous cell carcinoma.
Charlotte Leduc,Charlotte Leduc,Julien Adam,Emilie Louvet,Emilie Louvet,Tony Sourisseau,Tony Sourisseau,Nicolas Dorvault,Nicolas Dorvault,Marine Bernard,Marine Bernard,Elodie Maingot,Elodie Maingot,Laura Faivre,Mei-Shiue Cassin-Kuo,Mei-Shiue Cassin-Kuo,Emilie Boissier,Emilie Boissier,Marie-Charlotte Dessoliers,Marie-Charlotte Dessoliers,Angélique Robin,Angélique Robin,Odile Casiraghi,Caroline Even,Stéphane Temam,Ken A. Olaussen,Ken A. Olaussen,Jean-Charles Soria,Sophie Postel-Vinay +28 more
TL;DR: TPF induction chemotherapy in advanced HNSCC increases PD-L1 positivity on tumour-infiltrating ICs, as well as CD8+ lymphocytes density, which warrant independent validation on larger datasets and might help therapeutic strategy in advancedHNSCC.
Journal ArticleDOI
PARP1 impact on DNA repair of platinum adducts: preclinical and clinical read-outs.
Ken A. Olaussen,Ken A. Olaussen,Ken A. Olaussen,Julien Adam,Julien Adam,Julien Adam,Elsa Vanhecke,Elsa Vanhecke,Elsa Vanhecke,Philippe Vielh,Robert Pirker,Luc Friboulet,Luc Friboulet,Luc Friboulet,Helmut Popper,Angélique Robin,Angélique Robin,Angélique Robin,Frédéric Commo,Frédéric Commo,Frédéric Commo,Jürgen Thomale,Louis Kayitalire,Martin Filipits,Thierry Le Chevalier,Fabrice Andre,Fabrice Andre,Fabrice Andre,Elisabeth Brambilla,Jean-Charles Soria,Jean-Charles Soria,Jean-Charles Soria +31 more
TL;DR: It is confirmed that platinum DNA adduct accumulation is linked to chemosensitivity, which increase by pharmacological PARP inhibitors points to a role of PARP-dependent DNA repair in the process.