J
Jeanne Yue
Publications - 3
Citations - 451
Jeanne Yue is an academic researcher. The author has contributed to research in topics: Cancer & Genomics. The author has an hindex of 2, co-authored 2 publications receiving 245 citations.
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Journal ArticleDOI
High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.
Pedram Razavi,Bob T. Li,David N Brown,Byoungsok Jung,Earl Hubbell,Ronglai Shen,Wassim Abida,Krishna Juluru,Ino de Bruijn,Chenlu Hou,Oliver Venn,Raymond S. Lim,Aseem Anand,Tara Maddala,Sante Gnerre,Ravi Vijaya Satya,Qinwen Liu,Ling Shen,Nicholas Eattock,Jeanne Yue,Alexander W. Blocker,Mark Lee,Amy J. Sehnert,Hui Xu,Megan P. Hall,Angie Santiago-Zayas,William Novotny,James M. Isbell,Valerie W. Rusch,George Plitas,Alexandra S. Heerdt,Marc Ladanyi,David M. Hyman,David R. Jones,Monica Morrow,Gregory J. Riely,Howard I. Scher,Charles M. Rudin,Mark E. Robson,Luis A. Diaz,David B. Solit,Alex Aravanis,Jorge S. Reis-Filho +42 more
TL;DR: Ultra-sensitive cell-free DNA (cfDNA) sequencing uncovers clonal hematopoiesis as a major source of somatic cfDNA variants in healthy individuals and patients with cancer, and underscores the importance of matched white blood cell DNA sequencing in liquid biopsy procedures.
Proceedings ArticleDOI
Abstract LB-343: Development of plasma cell-free DNA (cfDNA) assays for early cancer detection: first insights from the Circulating Cell-Free Genome Atlas Study (CCGA)
Alex Aravanis,Geoffrey R. Oxnard,Tara Maddala,Earl Hubbell,Oliver Venn,Arash Jamshidi,Ling Shen,Hamed Amini,John A. Beausang,Craig Betts,Daniel Civello,Konstantin Davydov,Saniya Fazullina,Darya Filippova,Sante Gnerre,Samuel Gross,Chenlu Hou,Roger Jiang,Byoungsok Jung,Kathryn N. Kurtzman,Collin Melton,Shivani Nautiyal,Jonathan Newman,Joshua Newman,Cosmos Nicolaou,Richard P. Rava,Onur Sakarya,Ravi Vijaya Satya,Seyedmehdi Shojaee,Kristan Steffen,Anton Valouev,Hui Xu,Jeanne Yue,Nan Zhang,José Baselga,Rosanna Lapham,Daron G. Davis,David J. Smith,Donald A. Richards,Michael V. Seiden,Charles Swanton,Timothy J. Yeatman,Robert Tibshirani,Christina Curtis,Sylvia K. Plevritis,Richard J. Williams,Eric A. Klein,Anne-Renee Hartman,Minetta C. Liu +48 more
TL;DR: A consistent “cancer-like” signal was observed in 99% specificity for invasive cancer, and support the promise of cfDNA assay for early cancer detection, as well as learnings from multiple cfDNA assays reported here.