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Ino de Bruijn

Researcher at Memorial Sloan Kettering Cancer Center

Publications -  42
Citations -  6431

Ino de Bruijn is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Cancer & Biology. The author has an hindex of 20, co-authored 29 publications receiving 3951 citations. Previous affiliations of Ino de Bruijn include Science for Life Laboratory & Royal Institute of Technology.

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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Katherine A Hoadley, +738 more
- 05 Apr 2018 - 
TL;DR: Molecular similarities among histologically or anatomically related cancer types provide a basis for focused pan-cancer analyses, such as pan-gastrointestinal, Pan-gynecological, pan-kidney, and pan-squamous cancers, and those related by stemness features, which may inform strategies for future therapeutic development.
Journal ArticleDOI

Binning metagenomic contigs by coverage and composition

TL;DR: ConCOCT, a new algorithm that combines sequence composition and coverage across multiple samples, to automatically cluster contigs into genomes is presented, demonstrating high recall and precision on artificial as well as real human gut metagenome data sets.
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Genomic and Functional Approaches to Understanding Cancer Aneuploidy

Alison M. Taylor, +732 more
- 09 Apr 2018 - 
TL;DR: The genomic and phenotypic correlates of cancer aneuploidy are defined and genome engineering is applied to delete 3p in lung cells, causing decreased proliferation rescued in part by chromosome 3 duplication.
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Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

Matthew A. Bailey, +761 more
- 09 Aug 2018 - 
TL;DR: In this article, the authors made two errors in preparation of this manuscript and corrected them in the revised Figure S7 by re-ordering the mutations by frequency for COAD and READ independently.