J
Jeff Hardin
Researcher at University of Wisconsin-Madison
Publications - 120
Citations - 7346
Jeff Hardin is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Caenorhabditis elegans & Cadherin. The author has an hindex of 44, co-authored 113 publications receiving 6953 citations. Previous affiliations of Jeff Hardin include Fred Hutchinson Cancer Research Center & University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
A Putative Catenin–Cadherin System Mediates Morphogenesis of the Caenorhabditis elegans Embryo
TL;DR: This putative catenin–cadherin system is not essential for general cell adhesion in the C. elegans embryo, but rather mediates specific aspects of morphogenetic cell shape change and cytoskeletal organization.
Journal ArticleDOI
Cooperative regulation of AJM-1 controls junctional integrity in Caenorhabditis elegans epithelia
Mathias Köppen,Jeffrey S. Simske,Paul A. Sims,Bonnie L. Firestein,David H. Hall,Anthony D. Radice,Christopher Rongo,Jeff Hardin +7 more
TL;DR: It is concluded that LET-413 and DLG-1 cooperatively control AJM-1 localization and that AJM -1 controls the integrity of a distinct apical junctional domain in C. elegans.
Journal ArticleDOI
Cytokinesis and Midzone Microtubule Organization in Caenorhabditis elegans Require the Kinesin-like Protein ZEN-4
TL;DR: The identification of a null allele of zen-4, an MKLP1 homologue in the nematode Caenorhabditis elegans, is reported and it is demonstrated that ZEN-4 is essential for cytokinesis, suggesting that these microtubules are required for the completion of cytokineses.
Journal ArticleDOI
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos
Bruce W. Draper,Craig C. Mello,Bruce Bowerman,Jeff Hardin,James R. Priess,James R. Priess,James R. Priess +6 more
TL;DR: It is shown that maternal-effect lethal mutations in the gene mex-3 cause descendants of the anterior blastomere to produce muscles by a pattern of development similar to that of a descendant of the wild-type posterior Blastomere.
Journal ArticleDOI
The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans
TL;DR: It is shown that C. elegans vab-1 encodes a receptor tyrosine kinase of the Eph family, and that cell-cell interactions are required between neurons and epidermal cells for Epidermal morphogenesis.