J
Jeff Lapoint
Researcher at Kaiser Permanente
Publications - 12
Citations - 875
Jeff Lapoint is an academic researcher from Kaiser Permanente. The author has contributed to research in topics: Synthetic cannabinoids & Cannabinoid hyperemesis syndrome. The author has an hindex of 7, co-authored 12 publications receiving 781 citations. Previous affiliations of Jeff Lapoint include University of California, Irvine & New York University.
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Journal ArticleDOI
Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids
TL;DR: A review of the legal status of common synthetic cannabinoids detected in Spice and analytical procedures used to test Spice products and human specimens collected under a variety of clinical circumstances is provided in this paper.
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Severe Toxicity Following Synthetic Cannabinoid Ingestion
Jeff Lapoint,Laura P. James,Cindy L. Moran,Lewis S. Nelson,Robert S. Hoffman,Jeffery H. Moran +5 more
TL;DR: Ingestion of JWH-018 can produce seizures and tachyarrhythmias, and Clinicians, lawmakers, and the general public need to be aware of the potential for toxicity associated with synthetic cannabinoid use.
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Solid-Phase Extraction and Quantitative Measurement of Omega and Omega-1 Metabolites of JWH-018 and JWH-073 in Human Urine
Krishna C. Chimalakonda,Cindy L. Moran,Paul D. Kennedy,Gregory W. Endres,Adam Uzieblo,Paul J. Dobrowolski,Kim E. Fifer,Jeff Lapoint,Lewis S. Nelson,Robert S. Hoffman,Laura P. James,Anna Radominska-Pandya,Jeffery H. Moran +12 more
TL;DR: The liquid chromatography tandem mass spectrometry procedure coupled with an automated solid-phase extraction procedure incorporating deuterium-labeled internal standards provides rapid resolution of the (ω)- and (ω-1) metabolites with adequate sensitivity, precision, and accuracy for trace analysis in human urine.
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Cannabinoid Hyperemesis Syndrome: Public Health Implications and a Novel Model Treatment Guideline
Jeff Lapoint,Seth Meyer,Charles K. Yu,Kristi L. Koenig,Roneet Lev,Sayone Thihalolipavan,Katherine Staats,Christopher A. Kahn +7 more
TL;DR: A novel treatment guideline is presented that highlights the identification and diagnosis of Cannabinoid hyperemesis syndrome and summarizes treatment strategies aimed at resolution of symptoms, avoidance of unnecessary opioids, and ensuring patient safety.
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Cannabinoid hyperemesis syndrome: potential mechanisms for the benefit of capsaicin and hot water hydrotherapy in treatment
TL;DR: These complex interactions between the endocannabinoid systems and transient receptor potential vanilloid 1, in the setting of cannabinoid receptor desensitization, may yield important clues into the pathophysiology and treatment of cannabinoid hyperemesis syndrome.