J
Jenny M. Kelley
Researcher at National Institutes of Health
Publications - 21
Citations - 10706
Jenny M. Kelley is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & DNA sequencing. The author has an hindex of 17, co-authored 21 publications receiving 10510 citations. Previous affiliations of Jenny M. Kelley include Philips.
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Journal ArticleDOI
The complete genome sequence of the gastric pathogen Helicobacter pylori
Jean-F. Tomb,Owen White,Anthony R. Kerlavage,Rebecca A. Clayton,Granger G. Sutton,Robert D. Fleischmann,Karen A. Ketchum,Hans-Peter Klenk,Steven R. Gill,Brian Dougherty,Karen E. Nelson,John Quackenbush,Lixin Zhou,Ewen F. Kirkness,Scott N. Peterson,Brendan J. Loftus,Delwood Richardson,Robert J. Dodson,Hanif Khalak,Anna Glodek,Keith McKenney,Lisa M. Fitzegerald,Norman H. Lee,Mark Raymond Adams,Erin Hickey,Douglas E. Berg,Jeanine D. Gocayne,Teresa Utterback,Jeremy Peterson,Jenny M. Kelley,Matthew D. Cotton,J. Weidman,Claire Fujii,Cheryl Bowman,Larry Watthey,Erik Wallin,William S. Hayes,Mark Borodovsky,Peter D. Karp,Hamilton O. Smith,Claire M. Fraser,J. Craig Venter +41 more
TL;DR: Sequence analysis indicates that H. pylori has well-developed systems for motility, for scavenging iron, and for DNA restriction and modification, and consistent with its restricted niche, it has a few regulatory networks, and a limited metabolic repertoire and biosynthetic capacity.
Journal ArticleDOI
The minimal gene complement of Mycoplasma genitalium
Claire M. Fraser,Jeannine D. Gocayne,Owen White,Mark Raymond Adams,Rebecca A. Clayton,Robert D. Fleischmann,Carol J. Bult,Anthony R. Kerlavage,Granger G. Sutton,Jenny M. Kelley,Janice L. Fritchman,Janice Weidman,Keith V. Small,Mina Sandusky,Joyce Fuhrmann,David Nguyen,Teresa Utterback,D. Saudek,Cheryl Phillips,Joseph M. Merrick,J F Tomb,Brian Dougherty,Kenneth F. Bott,Ping Chuan Hu,Thomas Lucier,Scott N. Peterson,Hamilton O. Smith,Clyde A. Hutchison,J. Craig Venter +28 more
TL;DR: Comparison of the Mycoplasma genitalium genome to that of Haemophilus influenzae suggests that differences in genome content are reflected as profound differences in physiology and metabolic capacity between these two organisms.
Journal ArticleDOI
Complementary DNA sequencing : expressed sequence tags and human genome project
Mark Raymond Adams,Jenny M. Kelley,Jeannine D. Gocayne,Mark Dubnick,Mihael H. Polymeropoulos,Hong Xiao,Carl R. Merril,Andrew Wu,Bjorn Olde,Ruben F. Moreno,Anthony R. Kerlavage,W. Richard McCombie,J. Craig Venter +12 more
TL;DR: Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs), which will facilitate the tagging of most human genes in a few years at a fraction of the cost of complete genomic sequencing.
Journal ArticleDOI
Sequence identification of 2,375 human brain genes.
Mark Raymond Adams,Mark Dubnick,Anthony R. Kerlavage,Ruben F. Moreno,Jenny M. Kelley,Teresa Utterback,James W. Nagle,Chris Fields,J. Craig Venter +8 more
TL;DR: 2,672 new, independent cDNA clones isolated from four human brain cDNA libraries are partially sequenced to generate 2,375 expressed sequence tags to nuclear-encoded genes, representing an approximate doubling of the number of human genes identified by DNA sequencing and may represent as many as 5% of the genes in the human genome.
Journal ArticleDOI
High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Kenneth H. Buetow,Michael N. Edmonson,Richard Macdonald,Robert J. Clifford,Ping Yip,Jenny M. Kelley,Daniel P. Little,Robert L. Strausberg,Hubert Koester,Charles R. Cantor,Andreas Braun +10 more
TL;DR: This system couples informatics tools that mine candidate SNPs from public expressed sequence tag resources and automatically designs assay reagents with detection by a chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry platform to provide preliminary insights into patterns of polymorphism in a genomewide collection of gene-based polymorphisms.