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Jeremy A. Squire

Researcher at University of São Paulo

Publications -  349
Citations -  41173

Jeremy A. Squire is an academic researcher from University of São Paulo. The author has contributed to research in topics: Comparative genomic hybridization & Fluorescence in situ hybridization. The author has an hindex of 87, co-authored 344 publications receiving 38764 citations. Previous affiliations of Jeremy A. Squire include University of Toronto & Kingston General Hospital.

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A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195

B.J. Eigl, +15 more
- 19 May 2015 - 
TL;DR: Although SB939 was tolerable at the dose/schedule given, and showed declines in CTC in the majority of evaluable patients, it did not show sufficient activity based on PSA RR to warrant further study as a single agent in unselected patients with CRPC.
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The human UDP‐N‐Acetylglucosamine:α‐6‐d‐Mannoside‐β‐1,2‐N‐Acetylglucosaminyltransferase II Gene (MGAT2)

Jenny Tan, +7 more
- 01 Jul 1995 - 
TL;DR: Northern analysis of restriction enzyme digests of human genomic DNA indicates that there is only a single copy of the MGAT2 gene and there is no sequence similarity to any previously cloned glycosyltransferases including human UDP-GlcNAc-T I and II.
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Identification of a novel gene NCRMS on chromosome 12q21 with differential expression between rhabdomyosarcoma subtypes.

Agnes S. Chan, +4 more
- 02 May 2002 - 
TL;DR: This work has identified the novel gene NCRMS (non-coding RNA in RMS) that has increased expression in the alveolar subtype relative to the embryonal subtype, and it is likely thatNCRMS is a functional non-c coding RNA.
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Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13

Jeremy A. Squire, +9 more
- 01 Sep 1986 - 
TL;DR: Cloning the ESD gene from a human cDNA library by using oligonucleotides specific for a partial amino acid sequence of the purified enzyme to provide a genetic marker for further studies on retinoblastoma reveals restriction fragment length polymorphism with Apa I.
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PTEN-deficient prostate cancer is associated with an immunosuppressive tumor microenvironment mediated by increased expression of IDO1 and infiltrating FoxP3+ T regulatory cells.

Thiago Vidotto, +11 more
- 01 Jun 2019 - 
TL;DR: Loss of the PTEN tumor suppressor gene is observed in 20% to 30% of prostate cancers (PCa) when first detected and the rate increases with PCa progression and advanced disease.