J
Jeremy A. Squire
Researcher at University of São Paulo
Publications - 349
Citations - 41173
Jeremy A. Squire is an academic researcher from University of São Paulo. The author has contributed to research in topics: Comparative genomic hybridization & Fluorescence in situ hybridization. The author has an hindex of 87, co-authored 344 publications receiving 38764 citations. Previous affiliations of Jeremy A. Squire include University of Toronto & Kingston General Hospital.
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Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer
TL;DR: The findings indicate that genomic deletions of PTEN fall into five different size distributions, with breakpoints that often occur close LCR regions, and that each subtype is associated with a characteristic aneuploidy signature.
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Reduced tumorigenesis in p53 knockout mice exposed in utero to low‐dose vitamin E
TL;DR: The limited antioxidative capacity of the fetus renders it more susceptible to reactive oxygen species (ROS), and possibly to ROS‐mediated cancer initiation or promotion in utero.
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High definition cytogenetics and oligonucleotide aCGH analyses of cisplatin‐resistant ovarian cancer cells
Mona Prasad,Marcus Q. Bernardini,Anya Tsalenko,Paula Marrano,Jana Paderova,Chung Hae Lee,Amir Ben-Dor,Michael T. Barrett,Michael T. Barrett,Jeremy A. Squire,Jeremy A. Squire +10 more
TL;DR: In this article, the authors applied molecular cytogenetic analyses including spectral karyotyping, multicolor banding, and fluorescence in situ hybridization with aCGH to comprehensively investigate the genomic aberrations associated with cisplatin resistance in A2780 ovarian cancer cells.
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Interphase cytogenetic analysis of in vivo differentiation in the myelodysplasia of Down syndrome
TL;DR: Archival peripheral blood and/or bone marrow films of six patients with Down syndrome and MDS whose leukemic cells contained monosomy 7 or trisomy 8 were studied, providing evidence that the abnormal cell in MDS is a progenitor cell with the potential of forming cells of megakaryocyte and erythroid lineages.
Journal Article
Identification of NKIAMRE, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion
TL;DR: NKIAMRE, a novel cyclin-dependent kinase-related molecule that is closely related to the rat serine/threonine kinase NKIATRE, is identified and may be an important determinant of dysmyelopoiesis.