J
Jeremy A. Squire
Researcher at University of São Paulo
Publications - 349
Citations - 41173
Jeremy A. Squire is an academic researcher from University of São Paulo. The author has contributed to research in topics: Comparative genomic hybridization & Fluorescence in situ hybridization. The author has an hindex of 87, co-authored 344 publications receiving 38764 citations. Previous affiliations of Jeremy A. Squire include University of Toronto & Kingston General Hospital.
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Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma
Georges Maire,Maisa Yoshimoto,Susan Chilton-MacNeill,Paul S. Thorner,Maria Zielenska,Jeremy A. Squire +5 more
TL;DR: There was a marked association between increased overall levels of S-CIN, determined by copy number transition frequency and higher levels of RECQL4, and there was no evidence that disruption of 8q24 in OS led to an elevated expression ofRECQL4.
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Loss of Imprinting of Human Insulin-like Growth Factor II Gene, IGF2, in Acute Myeloid Leukemia
TL;DR: Constitutional loss of monoallelic expression in 50% of the leukemia samples tested suggests that abnormal imprinting of IGF2 could play an important role in either leukemogenesis or cytokine dysregulation for leukemic cells.
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Structural characterization and mapping of the normal epithelial cell-specific 1 gene.
Liu-Ying Luo,Liu-Ying Luo,Jo-Anne Herbrick,Stephen W. Scherer,Barbara G. Beatty,Barbara G. Beatty,Jeremy A. Squire,Jeremy A. Squire,Eleftherios P. Diamandis,Eleftherios P. Diamandis +9 more
TL;DR: The results suggest that the NES1 gene originates from the same ancestor as trypsinogen, PSA, and TPA, but remains in close proximity to PSA.
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Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery
Muhammad Nawaz,Farah Fatima,Irina Nazarenko,Karin M. Ekström,Iram Murtaza,Mariam Anees,Aneesa Sultan,Luciano Neder,Giovanni Camussi,Hadi Valadi,Jeremy A. Squire,Thomas Kislinger +11 more
TL;DR: A deeper understanding of ovarian cancer-derived EVs, the types of cargo molecules and their biological roles in cancer growth, metastases and drug resistance, could have significant impact on the discovery of novel biomarkers and innovative therapeutics.
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Acquisition of secondary structural chromosomal changes in pediatric ewing sarcoma is a probable prognostic factor for tumor response and clinical outcome.
Maria Zielenska,Zong Mei Zhang,Zong Mei Zhang,Kwan Ng,Paula Marrano,Paula Marrano,Jane Bayani,Jane Bayani,Jane Bayani,Oswaldo C. Ramirez,Poul H. Sorensen,Paul S. Thorner,Mark T. Greenberg,Jeremy A. Squire +13 more
TL;DR: The Ewing sarcoma group of tumors commonly have the t(11;22)(q24;q12) or other rearrangements involving 22q12, namely gains of chromosomes 8 and 12, the unbalanced translocation t(1;16), and deleting at the short arm of chromosome 1.