J
Jernej Mlakar
Researcher at University of Ljubljana
Publications - 25
Citations - 2952
Jernej Mlakar is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Biology & Glioma. The author has an hindex of 8, co-authored 18 publications receiving 2558 citations.
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Journal ArticleDOI
Zika Virus Associated with Microcephaly
Jernej Mlakar,Miša Korva,Mateja Poljšak-Prijatelj,Jerica Mraz,Marko Kolenc,Katarina Resman Rus,Tina Vesnaver Vipotnik,Vesna Fabjan,Alenka Vizjak,Miroslav Petrovec +9 more
TL;DR: The case of an expectant mother who had a febrile illness with rash at the end of the first trimester of pregnancy while she was living in Brazil and revealed microcephaly with calcifications in the fetal brain and placenta is described.
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Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia
Marco Onorati,Zhen Li,Fuchen Liu,André M. M. Sousa,Naoki Nakagawa,Mingfeng Li,Maria Teresa Dell’Anno,Forrest O. Gulden,Sirisha Pochareddy,Andrew T.N. Tebbenkamp,Wenqi Han,Mihovil Pletikos,Tianliuyun Gao,Ying Zhu,Candace Bichsel,Luis Varela,Klara Szigeti-Buck,Steven Lisgo,Yalan Zhang,Anze Testen,Xiao-Bing Gao,Jernej Mlakar,Mara Popović,Marie Flamand,Stephen M. Strittmatter,Leonard K. Kaczmarek,Eva S. Anton,Tamas L. Horvath,Brett D. Lindenbach,Nenad Sestan +29 more
TL;DR: It is shown that ZIKV infects both neocortical and spinal cord neuroepithelial stem cells as well as their fetal homolog, radial glial cells (RGCs), causing disrupted mitoses, supernumerary centrosomes, structural disorganization, and cell death.
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Zika Virus–Associated Micrencephaly: A Thorough Description of Neuropathologic Findings in the Fetal Central Nervous System
Peter Štrafela,Alenka Vizjak,Jerica Mraz,Jernej Mlakar,Jože Pižem,Nataša Tul,Tatjana Avšič Županc,Mara Popović +7 more
TL;DR: The findings are in agreement with neuroimaging of Zika virus-associated fetal and infant micrencephalic brains and, to some extent, with neuroIMaging of other intrauterine infections causing microcephaly.
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Brain invasion assessability in meningiomas is related to meningioma size and grade, and can be improved by extensive sampling of the surgically removed meningioma specimen.
TL;DR: Meningioma grade, size and number of tissue blocks were independent predictors of brain invasion assessability and can be improved by extensive sampling of meningioma surgical.
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CCR5-Mediated Signaling Is Involved in Invasion of Glioblastoma Cells in Its Microenvironment.
Metka Novak,Miha Koprivnikar Krajnc,Barbara Hrastar,Barbara Breznik,Bernarda Majc,Mateja Mlinar,Ana Rotter,Andrej Porčnik,Jernej Mlakar,Katja Stare,Richard G. Pestell,Tamara Lah Turnšek +11 more
TL;DR: Autocrine and paracrine cross-talk in glioblastoma and, in particular, gli oblastoma stem cells with its stromal microenvironment, involves CCR5 and CCL5, contributing to gliOBlastoma invasion, suggesting the CCL 5/CCR5 axis as a potential therapeutic target that can be targeted with repositioned drug maraviroc.