J
Jiang-Jiang Qin
Researcher at Chinese Academy of Sciences
Publications - 177
Citations - 4538
Jiang-Jiang Qin is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 31, co-authored 138 publications receiving 3139 citations. Previous affiliations of Jiang-Jiang Qin include Texas Tech University Health Sciences Center & Second Military Medical University.
Papers
More filters
Journal ArticleDOI
The MDM2-p53 pathway revisited.
TL;DR: This review aims to highlight the multifaceted network of molecules regulating the MDM2-p53 axis to better understand the pathway and exploit it for anticancer therapy.
Journal ArticleDOI
Ginsenosides as anticancer agents: in vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action
TL;DR: Recent advances in the discovery and evaluation of ginsenosides as cancer therapeutic agents support further pre-clinical and clinical development of these agents for the treatment of primary and metastatic tumors.
Journal ArticleDOI
STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review
TL;DR: This review discusses the recent advances in the understanding of STAT3, with a focus on STAT3’s oncogenic role in TNBC and proposes potential strategies that can be further examined for developing more specific and effective inhibitors for TNBC prevention and therapy.
Journal ArticleDOI
Long non-coding RNAs towards precision medicine in gastric cancer: early diagnosis, treatment, and drug resistance
Li Yuan,Zhiyuan Xu,Shan-Ming Ruan,Shaowei Mo,Jiang-Jiang Qin,Jiang-Jiang Qin,Xiang-Dong Cheng +6 more
TL;DR: The present review focuses on the clinical potential of lncRNAs as biomarkers in liquid biopsies in the diagnosis and prognosis of gastric cancer and comprehensively discusses the roles of lNCRNAs and their molecular mechanisms in Gastric cancer chemoresistance as well as their potential as therapeutic targets for gastriccancer precision medicine.
Journal ArticleDOI
Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update.
Jinyun Dong,Zuodong Qin,Weidong Zhang,Gang Cheng,Assaraf G. Yehuda,Charles R. Ashby,Zhe-Sheng Chen,Xiang-Dong Cheng,Jiang-Jiang Qin,Jiang-Jiang Qin +9 more
TL;DR: A comprehensive review of the synthetic and natural products that have specific inhibitory activity on P-gp drug efflux as well as promising chemosensitizing efficacy in MDR cancer cells is provided.