scispace - formally typeset
J

Jie Fan

Researcher at University of Pittsburgh

Publications -  84
Citations -  10766

Jie Fan is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Inflammation & Lung injury. The author has an hindex of 38, co-authored 78 publications receiving 8532 citations. Previous affiliations of Jie Fan include Veterans Health Administration.

Papers
More filters
Journal ArticleDOI

atf4 promotes β-catenin expression and osteoblastic differentiation of bone marrow mesenchymal stem cells.

Shibing Yu, +7 more
- 01 Jan 2013 - 
TL;DR: It is shown that activating transcription factor 4 (ATF4) plays a critical role in promoting bone marrow MSC differentiation towards the osteoblast lineage and establishes a new role of ATF4 in controlling the β-catenin protein levels and MSC differentiate towards the bone marrow lineage.
Journal ArticleDOI

Interacting Neuroendocrine and Innate and Acquired Immune Pathways Regulate Neutrophil Mobilization from Bone Marrow following Hemorrhagic Shock

Yujian Liu, +8 more
- 01 Jan 2009 - 
TL;DR: Data indicate that HS/R, a global ischemia/reperfusion stimulus, regulates PMN mobilization through a series of interacting pathways that include neuroendocrine and innate and acquired immune systems.
Journal ArticleDOI

Injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages

Juan Wang, +11 more
- 01 Jan 2015 - 
TL;DR: A novel signaling mechanism that controls IP‐10 expression in monocytes/macrophages by MRP8/MRP14 is identified, which may play an important role in injury‐induced inflammation.
Journal ArticleDOI

Hemorrhagic Shock Augments Nlrp3 Inflammasome Activation in The Lung through Impaired Pyrin Induction

Peng Xu, +16 more
- 15 May 2013 - 
TL;DR: A novel mechanism by which HS suppresses negative-feedback regulation of Nlrp3 inflammasome to enhance IL-1β secretion in response to subsequent LPS challenge and so primes for inflammation is demonstrated.
Journal ArticleDOI

Anti-fibrotic effect of thymoquinone on hepatic stellate cells

Mohammed Ghazwani, +5 more
- 15 Feb 2014 - 
TL;DR: The results showed that pretreatment of mice with TQ has protective effect against CCl4-induced liver injury compared to control group (untreated), which is consistent with previous studies, and suggests that T Q has a direct effect on HSCs, which may contribute to its overall antifibrotic effect.