Guozhi Xiao

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Interestingly, subclones with both high and low differentiation potential produced similar amounts of collagen in culture and expressed comparable basal levels of mRNA encoding Osf2/Cbfa1, an osteoblast‐related transcription factor, and there was no clear relationship between levels of this message and induction of mRNAs for other differentiation markers.

TL;DR: This study is the first demonstration that Cbfa1 is controlled by MAPKs and suggests that this pathway has an important role in the control of osteoblast-specific gene expression.

TL;DR: Findings suggest that Runx2 plays a central role in coordinating multiple signals involved in osteoblast differentiation and post‐translational modifications such as phosphorylation may influence interactions between Runx 2 and other nuclear factors.

TL;DR: It is demonstrated that HAP imparts osteoconductivity and the highly porous PLLA/HAP composite scaffolds are superior to pure PLLa scaffolds for bone tissue engineering.