J
Jihye Kim
Researcher at Anschutz Medical Campus
Publications - 240
Citations - 4244
Jihye Kim is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 29, co-authored 160 publications receiving 3184 citations. Previous affiliations of Jihye Kim include University of Colorado Denver & University of Colorado Boulder.
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Journal ArticleDOI
The transcriptional landscape and mutational profile of lung adenocarcinoma
Jeong-Sun Seo,Young Seok Ju,Won-Chul Lee,Jong Yeon Shin,June Koo Lee,Thomas Bleazard,Junho Lee,Yoo Jin Jung,Jung Oh Kim,Jung Young Shin,Saet Byeol Yu,Jihye Kim,Eung Ryoung Lee,Chang Hyun Kang,In Kyu Park,Hwanseok Rhee,Se-Hoon Lee,Jong Il Kim,Jin Hyoung Kang,Young Tae Kim,Young Tae Kim,Young Tae Kim +21 more
TL;DR: The first large scale RNA sequencing study of lung adenocarcinoma is presented, demonstrating its power to identify somatic point mutations as well as transcriptional variants such as gene fusions, alternative splicing events, and expression outliers.
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Retroperitoneal Cystic Masses: CT, Clinical, and Pathologic Findings and Literature Review
TL;DR: Although there is substantial overlap of computed tomographic (CT) findings in various retroperitoneal cysts, some CT features, along with clinical characteristics, may suggest a specific diagnosis.
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DSigDB: drug signatures database for gene set analysis
Minjae Yoo,Jimin Shin,Jihye Kim,Karen A. Ryall,Kyubum Lee,Sunwon Lee,Minji Jeon,Jaewoo Kang,Aik Choon Tan +8 more
TL;DR: The creation of Drug Signatures Database (DSigDB), a new gene set resource that relates drugs/compounds and their target genes, for gene set enrichment analysis (GSEA) is reported.
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Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.
Shanshan Pei,Daniel A. Pollyea,Annika Gustafson,Brett M. Stevens,Mohammad Minhajuddin,Rui Fu,Kent Riemondy,Austin E. Gillen,Ryan M. Sheridan,Jihye Kim,James C. Costello,Maria L. Amaya,Anagha Inguva,Amanda Winters,Haobin Ye,Anna Krug,Courtney L. Jones,Biniam Adane,Nabilah Khan,J Ponder,Jeffrey Schowinsky,Diana Abbott,Andrew Hammes,Jason R. Myers,John M. Ashton,Travis Nemkov,Angelo D'Alessandro,Jonathan A. Gutman,Haley E. Ramsey,Michael R. Savona,Clayton A. Smith,Craig T. Jordan +31 more
TL;DR: It is concluded that resistance to venetoclax + azacitidine can arise due to biological properties intrinsic to monocytic differentiation, and it is proposed that optimal AML therapies should be designed so as to independently target AML subclones that may arise at differing stages of pathogenesis.
Journal ArticleDOI
Tankyrase and the Canonical Wnt Pathway Protect Lung Cancer Cells from EGFR Inhibition
Matias Casás-Selves,Jihye Kim,Zhiyong Zhang,Barbara Helfrich,Dexiang Gao,Christopher C. Porter,Hannah Scarborough,Paul A. Bunn,Daniel C. F. Chan,Aik Choon Tan,James DeGregori +10 more
TL;DR: A critical role for tankyrase and the canonical Wnt pathway is revealed in maintaining lung cancer cells during EGFR inhibition and Targeting the Wnt-tankyrase-β-catenin pathway together with EG FR inhibition may improve clinical outcome in patients with NSCLC.