J
Jin-Yu Li
Researcher at Chinese Academy of Sciences
Publications - 17
Citations - 203
Jin-Yu Li is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Dendrobium & Mangostin. The author has an hindex of 7, co-authored 17 publications receiving 97 citations.
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Journal ArticleDOI
Structural characterization and hypoglycemic effect via stimulating glucagon-like peptide-1 secretion of two polysaccharides from Dendrobium officinale.
Meng-Ting Kuang,Jin-Yu Li,Yang Xiaobei,Liu Yang,Jing-Yue Xu,Yan Sha,Yongfeng Lv,Fu-Cai Ren,Jiang-Miao Hu,Jun Zhou +9 more
TL;DR: In vivo assays showed that D. officinale polysaccharides (DOPs) exerted significant hypoglycemic effects accompanying increased serum insulin and glucagon-like peptide-1 levels in streptozotocin-induced diabetic rats, and in vitro experiments indicated that DOPs may decrease fasting blood sugar levels by stimulating GLP-1 secretion and that intracellular DOP-induced GLPs involved the Ca2+/calmodulin/CaMKII and
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Stilbenes with anti-inflammatory and cytotoxic activity from the rhizomes of Bletilla ochracea Schltr.
Jin-Yu Li,Meng-Ting Kuang,Liu Yang,Qing-Hua Kong,Bo Hou,Zhenhua Liu,Xiao-Qian Chi,Ming-Yan Yuan,Jiang-Miao Hu,Jun Zhou +9 more
TL;DR: Four new dihydrophenanthrenofuran, bleochranols A-D, along with 21 known compounds including phenanthrenes and bibenzyls were isolated and elucidated from the rhizomes of Bletilla ochracea, showing remarkable cytotoxic activity against HL-60, A-549, and MCF-7 and anti-inflammatory activity against NO production in LPS-stimulated RAW 264.
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Phenolic Constituents with Antioxidative, Tyrosinase Inhibitory and Anti-aging Activities from Dendrobium loddigesii Rolfe.
Rui-Jing Ma,Liu Yang,Xue Bai,Jin-Yu Li,Ming-Yan Yuan,Ya-Qin Wang,Yong Xie,Jiang-Miao Hu,Jun Zhou +8 more
TL;DR: Results suggest that phenolic constituents from D. loddigesii may be candidate antioxidants, skin-whitening and/or anti-aging agents.
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Poly p-hydroxybenzyl substituted bibenzyls and phenanthrenes from Bletilla ochracea Schltr with anti-inflammatory and cytotoxic activity
Jin-Yu Li,Liu Yang,Bo Hou,Fu-Cai Ren,Yang Xiaobei,Yongfeng Lv,Meng-Ting Kuang,Jiang-Miao Hu,Jun Zhou +8 more
TL;DR: Ten previously undescribed stilbenoids, including six bibenzyls (bleochrins A-F, 1-6), three phenanthrenes derivatives (bleechrins G-J, 7-10) along with eleven known compounds were isolated from the rhizomes of Bletilla ochracea Schltr.
Journal ArticleDOI
Design, synthesis and structure–activity relationships of mangostin analogs as cytotoxic agents
Xiao-Qian Chi,Cheng-Ting Zi,Hong-Mei Li,Liu Yang,Yongfeng Lv,Jin-Yu Li,Bo Hou,Fu-Cai Ren,Jiang-Miao Hu,Jun Zhou +9 more
TL;DR: Structural–activity relationship analysis indicates that the maintenance of the isopentene group at C-8 is essential for the cytotoxic activity of mangostin.