J
Jing Mu
Researcher at National Institutes of Health
Publications - 20
Citations - 1039
Jing Mu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Singlet oxygen & Medicine. The author has an hindex of 12, co-authored 14 publications receiving 479 citations. Previous affiliations of Jing Mu include Peking University & Shenzhen University.
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Journal ArticleDOI
Development of endogenous enzyme-responsive nanomaterials for theranostics
TL;DR: This tutorial review summarizes the recent progress in endogenous enzyme-responsive nanomaterials based on different building blocks such as polymers, liposomes, small organic molecules, or inorganic/organic hybrid materials; their design principles are also elaborated.
Journal ArticleDOI
Solvent-Assisted Self-Assembly of a Metal-Organic Framework Based Biocatalyst for Cascade Reaction Driven Photodynamic Therapy.
Liangcan He,Liangcan He,Qianqian Ni,Jing Mu,Wenpei Fan,Lu Liu,Zhantong Wang,Ling Li,Wei Tang,Yijing Liu,Yaya Cheng,Longguang Tang,Zhen Yang,Yuan Liu,Jianhua Zou,Weijing Yang,Orit Jacobson,Fan Zhang,Pintong Huang,Xiaoyuan Chen +19 more
TL;DR: Inspired by biological transformation processes, effective biocatalytic cascades-driven photodynamic therapy in tumor-bearing mice is demonstrated by the integration of artificial enzyme with upconversion nanoparticles, providing Au-mediated cancer therapy via glucose oxidase-like catalytic activity.
Journal ArticleDOI
A Phototheranostic Strategy to Continuously Deliver Singlet Oxygen in the Dark and Hypoxic Tumor Microenvironment
Jianhua Zou,Jianhua Zou,Jianwei Zhu,Zhen Yang,Ling Li,Wenpei Fan,Liangcan He,Wei Tang,Liming Deng,Jing Mu,Yuanyuan Ma,Yaya Cheng,Wei Huang,Wei Huang,Xiaochen Dong,Xiaoyuan Chen +15 more
TL;DR: The designed phototheranostics could completely inhibit the tumor growth with the help of laser and provides a paradigm to develop highly efficient photosensitizers with photodynamic and photothermal capability for personalized cancer therapy.
Journal ArticleDOI
Activating Macrophage-Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles
Lang Rao,Shu-Kun Zhao,Shu-Kun Zhao,Churan Wen,Rui Tian,Lisen Lin,Bo Cai,Yue Sun,Fei Kang,Zhen Yang,Liangcan He,Jing Mu,Qian-Fang Meng,Guangyu Yao,Ni Xie,Xiaoyuan Chen +15 more
TL;DR: It is reported that genetically engineered cell‐membrane‐coated magnetic nanoparticles (gCM‐MNs) can disable both mechanisms that prevent macrophage phagocytosis of cancer cells and significantly prolong overall mouse survival.
Journal ArticleDOI
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy.
Wei Tang,Zhen Yang,Liangcan He,Liming Deng,Parinaz Fathi,Shoujun Zhu,Ling Li,Bo Shen,Zhantong Wang,Orit Jacobson,Jibin Song,Jianhua Zou,Ping Hu,Min Wang,Jing Mu,Yaya Cheng,Yuanyuan Ma,Longguang Tang,Wenpei Fan,Xiaoyuan Chen +19 more
TL;DR: In this paper, a hybrid semiconducting organosilica-based O2 nanoeconomizer pHPFON-NO/O2 was developed to combat tumor hypoxia.