Y
Yuan Liu
Researcher at National Institutes of Health
Publications - 83
Citations - 5942
Yuan Liu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Aptamer & Medicine. The author has an hindex of 33, co-authored 69 publications receiving 3872 citations. Previous affiliations of Yuan Liu include Chinese Academy of Sciences & Hong Kong University of Science and Technology.
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Journal ArticleDOI
Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy.
Lisen Lin,Tao Huang,Jibin Song,Xiangyu Ou,Zhangtong Wang,Hongzhang Deng,Rui Tian,Yijing Liu,Jun-Feng Wang,Yuan Liu,Guocan Yu,Zijian Zhou,Sheng Wang,Gang Niu,Huanghao Yang,Xiaoyuan Chen +15 more
TL;DR: The fabrication of copper peroxide (CP) nanodot is reported, which is the first example of a Fenton-type metal peroxide nanomaterial, and its use as an activatable agent for enhanced CDT by self-supplying H2O2.
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Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targeted Gene Regulation Therapy
Juan Li,Cheng Zheng,Sena Cansiz,Cuichen Wu,Jiehua Xu,Jiehua Xu,Cheng Cui,Yuan Liu,Weijia Hou,Yanyue Wang,Liqin Zhang,I-Ting Teng,Huanghao Yang,Weihong Tan,Weihong Tan +14 more
TL;DR: Y-gel-Apt strongly inhibited cell proliferation and migration in target A549 cells, but not in control cells, and holds great promise as a candidate for targeted gene or drug delivery and cancer therapy.
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Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins.
Ying Jiang,Ying Jiang,Muling Shi,Muling Shi,Yuan Liu,Yuan Liu,Shuo Wan,Cheng Cui,Liqin Zhang,Liqin Zhang,Weihong Tan,Weihong Tan +11 more
TL;DR: A sensor platform that profiles exosome surface proteins in minutes by the naked eye is reported that combines a gold nanoparticle complexed with a panel of aptamers and generates patterns for the identification of multiple proteins on the exosomes surface.
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Aptasensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes
Sai Wang,Liqin Zhang,Shuo Wan,Sena Cansiz,Cheng Cui,Yuan Liu,Yuan Liu,Ren Cai,Cheng-Yi Hong,I-Ting Teng,Muling Shi,Muling Shi,Yuan Wu,Yuan Wu,Yiyang Dong,Weihong Tan,Weihong Tan +16 more
TL;DR: The oriented immobilization of aptamers significantly improved the accessibility of an artificial nucleobase-containing aptamer to suspended exosome, and the NTH-assisted aptasensor could detect exosomes with 100-fold higher sensitivity when compared to the single-stranded aptamer-functionalized aptas sensor.
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A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live Cells
Cuichen Wu,Cuichen Wu,Sena Cansiz,Liqin Zhang,I-Ting Teng,Liping Qiu,Juan Li,Yuan Liu,Cuisong Zhou,Rong Hu,Tao Zhang,Cheng Cui,Liang Cui,Weihong Tan,Weihong Tan +14 more
TL;DR: This programmable cascade reaction presents a simple and modular amplification mechanism for intracellular biomarkers of interest, providing a significant boost to the search for clues leading to the accurate identification and effective treatment of cancers.