J
Jing Pu
Researcher at National Institutes of Health
Publications - 19
Citations - 2192
Jing Pu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Lipid droplet & Insulin resistance. The author has an hindex of 14, co-authored 15 publications receiving 1742 citations. Previous affiliations of Jing Pu include Chinese Academy of Sciences.
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Journal ArticleDOI
Mechanisms and functions of lysosome positioning
TL;DR: This work reviews recent findings on the mechanisms that mediate the motility and positioning of lysosomes, and the importance ofLysosome dynamics for cell physiology and pathology.
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BORC, a Multisubunit Complex that Regulates Lysosome Positioning
TL;DR: The identification of a multisubunit complex named BORC that regulates lysosome positioning is reported, which comprises eight subunits that functions to recruit the small GTPase Arl8 and promotes the kinesin-dependent movement of lysOSomes toward the plus ends of microtubules in the peripheral cytoplasm.
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A role for lipid droplets in inter-membrane lipid traffic.
John K. Zehmer,Youguo Huang,Gong Peng,Jing Pu,Richard G.W. Anderson,Pingsheng Liu,Pingsheng Liu +6 more
TL;DR: The lipid droplet‐associated membrane‐trafficking proteins are summarized and the evidence that lipid droplets interact with endoplasmic reticulum, endosomes, peroxisomes, and mitochondria is reviewed to present a model for how lipid Droplets can distribute lipids to specific membrane compartments.
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BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks.
TL;DR: Findings establish BORC as a master regulator of lysosome positioning through coupling to different kinesins and microtubule tracks that enables coordinate control of l Lysosome movement in different regions of the cell.
Journal ArticleDOI
Proteome of Skeletal Muscle Lipid Droplet Reveals Association with Mitochondria and Apolipoprotein A-I
Huina Zhang,Yang Wang,Jing Li,Jinhai Yu,Jing Pu,Linghai Li,Hongchao Zhang,Shuyan Zhang,Gong Peng,Fuquan Yang,Pingsheng Liu +10 more
TL;DR: The protein composition and characterization of skeletal muscle LDs are reported, and a novel LD-associated protein, apo A-I, the principal apolipoprotein of high density lipoprotein (HDL) particles, was also localized on skeletal muscleLDs.