Jitka Cejkova

TL;DR: The decrease of corneal antioxidant protective mechanisms results in oxidative injury of the cornea and causes damage of the inner parts of the eye by UVB rays and by reactive oxygen species generated by them.

TL;DR: Results show that BM‐MSCs' therapeutic effect on healing of injured corneal surface is comparable to that of tissue‐specific LSCs, and suggest that BM-MSCs can be used for ocular surface regeneration in cases when autologous L SCs are absent or difficult to obtain.

TL;DR: Repeated irradiation of the cornea with UVB rays evokes a deficiency in antioxidant enzymes in the corneal epithelium, which very probably contributes to the damage of thecornea (and possibly also deeper parts of the eye) fromUVB rays and the reactive oxygen products generated by them.

TL;DR: The role of oxidativestress in the pathogenesis of ocular diseases with particular attention to oxidative stress in the cornea and changes in corneal optical properties are discussed and advances in the treatment of corneAL oxidative injuries or diseases are shown.

TL;DR: MSCs on nanofiber scaffolds protected the formation of toxic peroxynitrite, lowered apoptotic cell death and decreased matrix metalloproteinase and pro-inflammatory cytokine production and significantly accelerated corneal healing.