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Jiyoun Lee

Researcher at Sungshin Women's University

Publications -  92
Citations -  2334

Jiyoun Lee is an academic researcher from Sungshin Women's University. The author has contributed to research in topics: Mitochondrial permeability transition pore & MPTP. The author has an hindex of 24, co-authored 87 publications receiving 1997 citations. Previous affiliations of Jiyoun Lee include Gwangju Institute of Science and Technology & Sookmyung Women's University.

Papers
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Journal ArticleDOI

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

Sarah E. Ewald, +5 more
- 11 Apr 2011 - 
TL;DR: TLR3, TLR7, and TLR9 are cleaved in the same step-wise manner in all immune cell types examined.
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Target deconvolution techniques in modern phenotypic profiling.

Jiyoun Lee, +1 more
- 01 Feb 2013 - 
TL;DR: This review will outline how both new and old techniques are being used in the difficult process of target identification and validation as well as discuss some of the ongoing challenges remaining for phenotypic screening.
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Functional imaging of legumain in cancer using a new quenched activity-based probe

Laura E. Edgington, +8 more
- 09 Jan 2013 - 
TL;DR: It is found that legumain activity is highly correlated with macrophage activation and furthermore that it is an ideal marker for primary tumor inflammation and early stage metastatic lesions.
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N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.

Jeewoo Lee, +20 more
- 30 May 2003 - 
TL;DR: Structural-activity analysis of the influence of modifications in the A- and C-regions of 4-methylsulfonamide ligands on VR1 agonism/antagonism indicated that 3-fluoro substitution inThe A-region and a 4-tert-butylbenzyl moiety in the C-region favored antagonism, whereas a 3-methoxy group in theA-region
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High Affinity Antagonists of the Vanilloid Receptor

Yun Wang, +9 more
- 01 Oct 2002 - 
TL;DR: It is concluded that JYL1421 is a competitive antagonist of rVR1, blocking response to all three of the agonists (capsaicin, heat, and protons) with enhanced potency relative to capsazepine.