João Costa Pessoa

TL;DR: This work reviews the medicinal applications proposed for vanadium compounds with particular emphasis on the more recent publications and concludes that the potential ofVanadium compounds to treat type 2 diabetes is still an open question and therapies using vanadium compound for e.g. antitumor and anti-parasitic related diseases remain promising.

TL;DR: There is no striking correlation between the nature of the ligand systems and the insulin-mimetic potency in these cell culture tests, encompassing 41 vanadium compounds, the results on 22 of which are reported in detail here.

TL;DR: The V-Salen and V-salan complexes show higher activity and normally better selectivity in alkene oxidation and higherActivity and enantioselectivity for sulfoxidation than their parent V- salen complexes, therefore being an advantageous alternative ligand system for oxidation catalysis.

TL;DR: The ability of vanadium to interfere with the metabolic processes involving Ca2+ and Mg2+, connected with its versatility to undergo changes in coordination geometry, allow V to influence the function of a large variety of phosphate-metabolizing enzymes and vanadate(V) salts and compounds have been frequently used either as inhibitors of these enzymes, or as probes to study the mechanisms of their reactions and catalytic cycle.

TL;DR: The results suggest that decomposition and subsequent ternary complex formation with endogenous or exogenous ligands in the organism affects the absorption efficacy of the originally neutral VO(IV) compounds considerably.