P
Peter K. Cheung
Researcher at University of British Columbia
Publications - 37
Citations - 1594
Peter K. Cheung is an academic researcher from University of British Columbia. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 18, co-authored 27 publications receiving 1401 citations. Previous affiliations of Peter K. Cheung include St. Paul's Hospital.
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Journal ArticleDOI
Molecular and Clinical Epidemiology of CXCR4-Using HIV-1 in a Large Population of Antiretroviral-Naive Individuals
Zabrina L. Brumme,Zabrina L. Brumme,James Goodrich,Howard Mayer,Chanson J. Brumme,Bethany M. Henrick,Brian Wynhoven,Jerome J. Asselin,Peter K. Cheung,Robert S. Hogg,Julio S. G. Montaner,Julio S. G. Montaner,P. Richard Harrigan,P. Richard Harrigan +13 more
TL;DR: Baseline CD4 cell count, pVL, HIV-1 V3 sequence, and CCR5 Delta 32 genotype were the strongest determinants of CXCR4-using HIV- 1 in this population of antiretroviral-naive individuals.
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Viremia, Fecal Shedding, and IgM and IgG Responses in Patients with Hepatitis E
Edward T. Clayson,Khin Saw Aye Myint,Rapin Snitbhan,David W. Vaughn,Bruce L. Innis,Lily Chan,Peter K. Cheung,Mrigendra P. Shrestha +7 more
TL;DR: Viremia, fecal shedding and antibody responses to hepatitis E virus (HEV) infections are poorly understood and are suggested to be a common occurrence in patients infected with HEV.
Journal ArticleDOI
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates
Tobias Sing,Andrew J. Low,Niko Beerenwinkel,Oliver Sander,Peter K. Cheung,Francisco S. Domingues,Joachim Büch,Martin Daumer,Rolf Kaiser,Thomas Lengauer,P. Richard Harrigan +10 more
TL;DR: An SVM-based approach that integrates sequence information with clinical and host data, resulting in improved performance and sensitivity compared with purely sequence-based approaches is presented.
Journal ArticleDOI
Homopolymer mutational hot spots mediate herpes simplex virus resistance to acyclovir.
Joe Sasadeusz,Frank Tufaro,S. Safrin,K Schubert,M M Hubinette,Peter K. Cheung,Stephen L. Sacks +6 more
TL;DR: It is demonstrated that the majority of ACVr clinical isolates contain frameshift mutations within two long homopolymer nucleotide stretches which function as hot spots within the HSV tk gene and produce nonfunctional, truncated TK proteins.
Journal ArticleDOI
Determining human immunodeficiency virus coreceptor use in a clinical setting: Degree of correlation between two phenotypic assays and a bioinformatic model
Katharina Skrabal,Andrew J. Low,Winnie Dong,Tobias Sing,Peter K. Cheung,Fabrizio Mammano,Fabrizio Mammano,P. Richard Harrigan +7 more
TL;DR: Two recombinant phenotypic assays for human immunodeficiency virus (HIV) coreceptor usage and an HIV envelope genotypic predictor were employed on a set of clinically derived HIV type 1 samples in order to evaluate the concordance between measures.