J
Joe Wooters
Publications - 4
Citations - 838
Joe Wooters is an academic researcher. The author has contributed to research in topics: Receptor & Signal transduction. The author has an hindex of 4, co-authored 4 publications receiving 749 citations.
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Journal ArticleDOI
PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3ζ signalosome and downstream signaling to PKCθ
Kelly-Ann Sheppard,Lori Fitz,Julie M. Lee,Christina Benander,Judith A. George,Joe Wooters,Yongchang Qiu,Jason Jussif,Laura L. Carter,Clive Wood,Divya Chaudhary +10 more
TL;DR: It is demonstrated that PD‐1 modulation of T‐cell function involves inhibition of TCR‐mediated phosphorylation of ZAP70 and association with CD3ζ andPD‐1 signaling attenuates PKCθ activation loop phosphorylated in a cognate TCR signal.
Journal ArticleDOI
Analysis of the human sperm proteome
TL;DR: This characterization of the human sperm proteome provides a high‐resolution, physiologically relevant index of the proteins that comprise human sperm.
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Endogenous Association of TRAF2, TRAF3, cIAP1, and Smac with Lymphotoxin β Receptor Reveals a Novel Mechanism of Apoptosis
TL;DR: The presence of cIAP1 and Smac in LIGHT·LTβR complex revealed a novel mechanism of LIGHT-induced apoptosis, and four of five proteins identified, TRAf2, TRAF3, cI AP1, and SmAC, are reported here.
Journal ArticleDOI
NAK Is Recruited to the TNFR1 Complex in a TNFα-dependent Manner and Mediates the Production of RANTES IDENTIFICATION OF ENDOGENOUS TNFR-INTERACTING PROTEINS BY A PROTEOMIC APPROACH
Jun Kuai,Joe Wooters,J. Perry Hall,Vikram R. Rao,Elliott Nickbarg,Bilian Li,Moitreyee Chatterjee-Kishore,Yongchang Qiu,Lih-Ling Lin +8 more
TL;DR: It is shown that NAK is recruited to TNFR1 in a temporally regulated and TNF alpha-dependent manner and that it mediates the TNFalpha-induced production of the chemokine RANTES (regulated on activation normal T cell expressed and secreted).