J
John A. McGrath
Researcher at King's College London
Publications - 674
Citations - 26684
John A. McGrath is an academic researcher from King's College London. The author has contributed to research in topics: Epidermolysis bullosa & Mutation. The author has an hindex of 75, co-authored 631 publications receiving 24078 citations. Previous affiliations of John A. McGrath include Ninewells Hospital & Southampton General Hospital.
Papers
More filters
Journal ArticleDOI
Somatic Forward (Nonrevertant) Mosaicism in Recessive Dystrophic Epidermolysis Bullosa
TL;DR: The use of topical rapamycin was well tolerated and resulted in the resolution of subungual tumors and rapid normalization of the overlying nail distortion in patients with ungual tumors associated with TSC, suggesting that topical Rapamycin is a safe, well-tolerated, and potentially efficacious treatment.
Journal ArticleDOI
Concurrent hidradenitis suppurativa and Dowling–Degos disease taken down a ‘Notch’
TL;DR: Four more individuals with HS–DDD are described and a founder mutation in PSENEN, which encodes a component of the c-secretase complex, is identified, which provides new insights into this particular ‘clinical collision’ and potentially offer new opportunities for improving patient management in the future.
Journal ArticleDOI
Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration
TL;DR: A role for Slac2-b in regulating local focal adhesion dynamics to support effective keratinocyte adhesion is supported and insight is provided into the underlying pathophysiology of inherited skin blistering.
Journal ArticleDOI
Transient bullous dermolysis of the newborn: a disorder of type VII collagen secretion?
Journal ArticleDOI
Molecular basis and inheritance patterns of amyloidosis cutis dyschromica.
F. P. C. Chiu,V Wessagowit,M. F. Cakmak,Brent J Doolan,T. Kootiratrakarn,P. Chaowalit,T. Bunnag,M. A. Simpson,John A. McGrath,Alexandros Onoufriadis +9 more
TL;DR: This work presents a new probabilistic analysis of the response of the immune system to corticosteroids to laser-spot removal, which has shown promise in predicting progeria and its role in disease progression.