John A. McGrath

TL;DR: Simple, pain-free treatment in patients using EMLA® cream for excessive granulation tissue occurring in dystropbic epidermolysis bullosa, junctional epiderMolysis Bullosa (non-Herlitz form) and pyoderma gangrenosum was used and clinical results were clearly superior to similar areas treated with a topical-steroid-antibiotic combination commonly used as a standard treatment.

TL;DR: Understanding the pathogenesis of HAE is leading to the introduction of new therapies that target the bradykinin receptor or inhibit kallikrein activity, innovations that will hopefully reduce morbidity and mortality in this group of severe genetic disease.

TL;DR: Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version.

TL;DR: Analysis of two induced pluripotent stem cell lines used in engineering of 3D human epidermal equivalent (HEE), which more closely approximates epidermis, found that differentiation and tissue formation may mitigate variations in the iPSC methylome.

TL;DR: This review aims to summarize both traditional and current strategies for identifying susceptibility and monogenetic disease genes and describes how these strategies have evolved in tune with the ever-expanding wealth of information now available at the authors' fingertips.