J
John F. Forbes
Researcher at University of Limerick
Publications - 373
Citations - 51254
John F. Forbes is an academic researcher from University of Limerick. The author has contributed to research in topics: Breast cancer & Tamoxifen. The author has an hindex of 88, co-authored 368 publications receiving 46433 citations. Previous affiliations of John F. Forbes include University of Newcastle & University of Melbourne.
Papers
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Proceedings ArticleDOI
Disease Related Outcome with Long Term Follow-Up: An Updated Analysis of the Intergroup Exemestane Study (IES).
Judith M Bliss,Lucy Kilburn,Robert E. Coleman,John F. Forbes,A. S. Coates,Stephen E. Jones,Jacek Jassem,Thierry Delozier,Jens O. Andersen,Robert Paridaens,R. C. Coombes +10 more
TL;DR: Analysis of breast cancer free survival (BCFS), censoring intercurrent deaths, provides a sensitive estimate of the true impact of an adjuvant intervention on breast cancer outcome.
Journal ArticleDOI
A phase I study of [225Ac]-FPI-1434 radioimmunotherapy in patients with IGF-1R expressing solid tumors.
Rosalyn A. Juergens,Katherine Zukotynski,Daniel Juneau,Lily Krnezich,Ryan Simms,John F. Forbes,Eric Burak,John F. Valliant,Lauren Stafford,Thomas Armor,István Molnár,Fred Saad +11 more
TL;DR: Type I insulin-like growth factor receptor (IGF-1R) is a transmembrane protein which is overexpressed in solid tumors including non–small cell lung, prostate, and breast cancers.
Journal ArticleDOI
Symptoms of endocrine treatment and outcome: A retrospective analysis of the monotherapy arms of the BIG 1-98 trial.
Jens Huober,Bernard F. Cole,Jimin Wu,Anita Giobbie-Hurder,Manuela Rabaglio,H. T. Mouridsen,L. Mauriac,John F. Forbes,Robert Paridaens,István Láng,I.E. Smith,Andrew M Wardley,Karen N. Price,A. Goldhirsch,A. S. Coates,Beat Thürlimann,Big Collaborative +16 more
TL;DR: Arthralgia/myalgia, but not vasomotor early symptoms, were associated with improved DFS, irrespective of endocrine treatment, in the BIG 1-98 trial.
Journal ArticleDOI
Trajectory optimization for flat dynamic systems
M. Guay,S. Kansal,John F. Forbes +2 more
TL;DR: This paper proposes an alternative method for solving dynamic optimization problems in which the nonlinear process model is flat, and exploits, as appropriate, either the differential flatness or the orbital flatness of the process model to explicitly eliminate the differential equations from the optimization problem.
Journal ArticleDOI
Intratumoral and plasma concentrations of gefitinib in breast cancer patients: Preliminary results from a presurgical investigatory study (BCIRG 103)
D. McKillop,G. Raab,Holger Eidtmann,A. Furnival,Alessandro Riva,John F. Forbes,John R. Mackey,M. P. Spence,M. Koehler,DJ Slamon +9 more
TL;DR: The pronounced tumour:plasma ratio (mean 54-fold) was much higher than that from the mouse xenograft model, and gefitinib tumour concentrations will also be compared with the biomarker data as they become available.