J
John H. Hammond
Researcher at University of Alabama at Birmingham
Publications - 3
Citations - 182
John H. Hammond is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Phosphorylation & Kinase. The author has an hindex of 3, co-authored 3 publications receiving 151 citations.
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Journal ArticleDOI
Postmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness
TL;DR: It is proposed that postmortem tissue is an underutilized substrate that may be used to translate genetic and/or preclinical studies, particularly for neuropsychiatric illnesses with complex etiologies, and thus serve as a useful vehicle for illustrating the challenges associated with this biological substrate.
Journal ArticleDOI
Abnormalities of signal transduction networks in chronic schizophrenia
Jennifer L. McGuire,Erica A K DePasquale,Adam J. Funk,Sinead M. O’Donnovan,Kathryn Hasselfeld,Shruti Marwaha,John H. Hammond,Vahram Hartounian,Vahram Hartounian,James H. Meador-Woodruff,Jarek Meller,Jarek Meller,Robert E. McCullumsmith +12 more
TL;DR: The data indicate subtle changes in kinase activity and regulation across an interlinked kinase network, suggesting signaling imbalances underlie the core symptoms of schizophrenia.
Journal ArticleDOI
Altered serine/threonine kinase activity in schizophrenia.
Jennifer L. McGuire,John H. Hammond,Stefani D. Yates,Dongquan Chen,Vahram Haroutunian,James H. Meador-Woodruff,Robert E. McCullumsmith +6 more
TL;DR: These data are the first to simultaneously investigate comprehensive changes in signaling cascades in a severe psychiatric disorder and the identification of novel substrates for drug discovery and the development of safer and more effective pharmacological treatment for schizophrenia.