J
John Matovu
Researcher at Makerere University
Publications - 5
Citations - 289
John Matovu is an academic researcher from Makerere University. The author has contributed to research in topics: Sputum & Tuberculosis. The author has an hindex of 5, co-authored 5 publications receiving 278 citations. Previous affiliations of John Matovu include University of California, San Francisco.
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Journal ArticleDOI
Sensitivity of direct versus concentrated sputum smear microscopy in HIV-infected patients suspected of having pulmonary tuberculosis
Adithya Cattamanchi,David W. Dowdy,J. Lucian Davis,William Worodria,William Worodria,Samuel Yoo,Moses M. Joloba,John Matovu,Philip C. Hopewell,Laurence Huang +9 more
TL;DR: Sputum concentration did not increase the sensitivity of light microscopy for TB diagnosis in this HIV-infected population and additional studies using maximal blinding, high-quality direct microscopy, and a rigorous gold standard should be conducted before universally recommending this technique.
Journal Article
Sensitivity and Specificity of Fluorescence Microscopy for Diagnosing Pulmonary Tuberculosis in a High HIV Prevalence Setting
Adithya Cattamanchi,J. L. Davis,William Worodria,S den Boon,S.D. Yoo,John Matovu,John Kiidha,F Nankya,Rachel Kyeyune,Patrick Byanyima,Alfred Andama,Moses Joloba,Dennis Osmond,Philip C. Hopewell,Laurence Huang +14 more
TL;DR: Although FM increases the sensitivity of sputum smear microscopy, additional data on FM specificity and on the clinical consequences associated with false-positive FM results are needed to guide implementation of this technology in high HIV prevalence settings.
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Mobile Digital Fluorescence Microscopy for Diagnosis of Tuberculosis
Asa Tapley,Neil A. Switz,Clay D. Reber,J. Lucian Davis,Cecily Miller,John Matovu,William Worodria,Laurence Huang,Daniel A. Fletcher,Adithya Cattamanchi +9 more
TL;DR: CellScope offers promise for expanding microscopy services when operated by health workers in low-resource settings, the feasibility of image transmission and analysis by experienced microscopists, and the accuracy of automated image analysis algorithms.
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Integrated Strategies to Optimize Sputum Smear Microscopy: A Prospective Observational Study
Adithya Cattamanchi,Laurence Huang,William Worodria,Saskia den Boon,Nelson Kalema,Winceslaus Katagira,Patrick Byanyima,Samuel Yoo,John Matovu,Philip C. Hopewell,J. Lucian Davis +10 more
TL;DR: In low-income, high TB burden settings, single-specimen microscopy and LED FM, either alone or in combination, could considerably increase identification of smear-positive TB cases.
Journal ArticleDOI
Poor Performance of Universal Sample Processing Method for Diagnosis of Pulmonary Tuberculosis by Smear Microscopy and Culture in Uganda
Adithya Cattamanchi,J. Lucian Davis,William Worodria,Samuel Yoo,John Matovu,John Kiidha,Florence Nankya,Rachel Kyeyune,Alfred Andama,Moses Joloba,Dennis Osmond,P. Hopewell,Laurence Huang +12 more
TL;DR: The results suggest that the USP method did not provide any significant advantage over the standard NALC method for conventional diagnosis of tuberculosis in the authors' setting and illustrate the importance of well-designed, field-level evaluations of novel diagnostic techniques.