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William Worodria
Researcher at Makerere University
Publications - 126
Citations - 3804
William Worodria is an academic researcher from Makerere University. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 26, co-authored 103 publications receiving 3279 citations. Previous affiliations of William Worodria include College of Health Sciences, Bahrain & Mulago Hospital.
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Journal ArticleDOI
Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study
Catharina Boehme,Mark P. Nicol,Mark P. Nicol,Pamela Nabeta,Joy Sarojini Michael,Eduardo Gotuzzo,Rasim Tahirli,Ma Tarcela Gler,Robert Blakemore,William Worodria,Christen Gray,Laurence Huang,Tatiana Cáceres,Rafail Mehdiyev,Lawrence Raymond,Andrew Whitelaw,Andrew Whitelaw,Kalaiselvan Sagadevan,Heather Alexander,Heather Alexander,Heidi Albert,Frank Cobelens,Helen M Cox,David Alland,Mark D. Perkins +24 more
TL;DR: The Xpert MTB/RIF test can effectively be used in low-resource settings to simplify patients' access to early and accurate diagnosis, thereby potentially decreasing morbidity associated with diagnostic delay, dropout and mistreatment.
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Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings.
Graeme Meintjes,Stephen D. Lawn,Stephen D. Lawn,Fabio Scano,Gary Maartens,Martyn A. French,William Worodria,Julian Elliott,David M Murdoch,Robert J. Wilkinson,Robert J. Wilkinson,Robert J. Wilkinson,Catherine Seyler,Laurence John,Maarten F. Schim van der Loeff,Peter Reiss,Lut Lynen,Edward N. Janoff,Charles F. Gilks,Robert Colebunders,Robert Colebunders +20 more
TL;DR: In this paper, consensus case definitions for paradoxical tuberculosis-associated IRIS, ART-associated tuberculosis, and unmasking tuberculosis associated IRIS were derived, which can be used by clinicians and researchers in a variety of settings to promote standardisation and comparability of data.
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HIV-Associated Pneumocystis Pneumonia
Laurence Huang,Adithya Cattamanchi,J. Lucian Davis,Saskia den Boon,Joseph A. Kovacs,Steven R. Meshnick,Robert F. Miller,Robert F. Miller,Peter D. Walzer,William Worodria,Henry Masur +10 more
TL;DR: Recent advances in the pathogenesis, epidemiology, diagnosis, and management of HIV-associated PCP and ongoing areas of clinical and translational research that are part of the IHOP study and the Longitudinal Studies of HIV and Lung Infections and Complications (Lung HIV).
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Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS.
Nicole A. Kruh-Garcia,Lisa M. Wolfe,Lelia H. Chaisson,William Worodria,Payam Nahid,Jeffrey S. Schorey,J. Lucian Davis,Karen M. Dobos +7 more
TL;DR: Development of targeted proteomics assays employing multiplexed multiple reaction monitoring mass spectrometry (MRM-MS) is described in order to allow us to follow those proteins previously identified by western blot or shotguns, and enhance biomarker discovery to include detection of Mtb proteins in human serum exosomes.
Journal ArticleDOI
Impact of Xpert MTB/RIF Testing on Tuberculosis Management and Outcomes in Hospitalized Patients in Uganda
Christina Yoon,Adithya Cattamanchi,J. Lucian Davis,William Worodria,Saskia den Boon,Nelson Kalema,Winceslaus Katagira,Sylvia Kaswabuli,Cecily Miller,Alfred Andama,Heidi Albert,Pamela Nabeta,Christen Gray,Irene Ayakaka,Laurence Huang +14 more
TL;DR: Xpert MTB/RIF facilitated more accurate and earlier TB diagnosis, leading to a higher proportion of TB suspects with a confirmed TB diagnosis prior to hospital discharge in a high HIV/low MDR TB prevalence setting, but the study did not detect a decrease in two-month mortality following implementation.