J
John Pluta
Researcher at University of Pennsylvania
Publications - 73
Citations - 5838
John Pluta is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Temporal lobe & Segmentation. The author has an hindex of 31, co-authored 70 publications receiving 4798 citations.
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Journal ArticleDOI
Multi-Atlas Segmentation with Joint Label Fusion
TL;DR: A new solution for the label fusion problem in which weighted voting is formulated in terms of minimizing the total expectation of labeling error and in which pairwise dependency between atlases is explicitly modeled as the joint probability of two atlas making a segmentation error at a voxel is proposed.
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The optimal template effect in hippocampus studies of diseased populations
Brian B. Avants,Paul A. Yushkevich,John Pluta,David L. Minkoff,Marc Korczykowski,John A. Detre,James C. Gee +6 more
TL;DR: The importance of the template increases when used to study pathology and may be less critical for normal control studies, as explicit geometric optimization of the shape component of the unbiased template positively impacts the study of diseased hippocampi.
Journal ArticleDOI
Automated Volumetry and Regional Thickness Analysis of Hippocampal Subfields and Medial Temporal Cortical Structures in Mild Cognitive Impairment
Paul A. Yushkevich,John Pluta,Hongzhi Wang,Long Xie,Songlin Ding,Eske Christiane Gertje,Eske Christiane Gertje,Lauren Mancuso,Daria Kliot,Sandhitsu R. Das,David A. Wolk +10 more
TL;DR: Thickness analysis results are consistent with volumetry, but provide additional regional specificity and suggest nonuniformity in the effects of aMCI on hippocampal subfields and MTL cortical subregions.
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Neural correlates of voluntary and involuntary risk taking in the human brain: an fMRI Study of the Balloon Analog Risk Task (BART).
TL;DR: These findings demonstrate the utility of the modified BART paradigms for using during fMRI to assess risk taking in the human brain, and suggest that recruitment of the brain mesolimbic-frontal pathway during risk-taking is contingent upon the agency of the risk taker.
Journal ArticleDOI
Integrated Molecular Characterization of Testicular Germ Cell Tumors
Hui Shen,Juliann Shih,Daniel P. Hollern,Linghua Wang,Reanne Bowlby,Satish K. Tickoo,Vesteinn Thorsson,Andrew J. Mungall,Yulia Newton,Apurva M. Hegde,Joshua Armenia,Francisco Sanchez-Vega,John Pluta,Louise C. Pyle,Rohit Mehra,Victor E. Reuter,Guilherme Godoy,Jeffrey A. Jones,Carl Simon Shelley,Darren R. Feldman,Daniel Onofre Vidal,Davor Lessel,Tomislav Kuliš,Flavio Mavignier Carcano,Kristen M. Leraas,Tara M. Lichtenberg,Denise Brooks,Andrew D. Cherniack,Juok Cho,David I. Heiman,Katayoon Kasaian,Minwei Liu,Michael S. Noble,Liu Xi,Hailei Zhang,Wanding Zhou,Jean C. Zenklusen,Carolyn M. Hutter,Ina Felau,Jiashan Zhang,Nikolaus Schultz,Gad Getz,Matthew Meyerson,Joshua M. Stuart,Rehan Akbani,David A. Wheeler,Peter W. Laird,Katherine L. Nathanson,Victoria K. Cortessis,Katherine A. Hoadley +49 more
TL;DR: High-dimensional analyses identified distinct molecular patterns that characterized the major recognized histologic subtypes of TGCT: seminoma, embryonal carcinoma, yolk sac tumor, and teratoma, and a subset of pure seminomas defined by KIT mutations, increased immune infiltration, globally demethylated DNA, and decreased KRAS copy number.