John T. O'Brien

TL;DR: Reductions in cortical FDG metabolism were present in newly diagnosed PD, and correlated with performance on neuropsychological tests, suggesting a reduced baseline parietal metabolism is associated with risk of cognitive decline and may represent a potential biomarker for this state and the development of PD dementia.

TL;DR: Pathologically distinct dementias exhibit characteristic patterns of regional volume loss compared with controls and other dementias, and Voxelwise differences identified in these cohorts highlight imaging signatures that may aid in the differentiation of dementia subtypes during life.

TL;DR: The term behavioral and psychological symptoms of dementia (BPSD) encompasses a diverse cluster of behavioral disturbances, such as restlessness (Hope et al., 1994), aggression (Patel & Hope, 1992), and shouting (Cohen-Mansfield & Werner, 1997), and a variety of psychiatric symptoms, including delusions, hallucinations, depression, and anxiety as mentioned in this paper.

TL;DR: A case for mild cognitive impairment inclusion in the Diagnostic and Statistical Manual of Mental Disorders (5th ed; DSM-V) is presented based on clinical, outcome, epidemiological, neuroimaging, and pathophysiological data.

TL;DR: Around 1 in 3 people with established dementia remain unrecognised, and around half of people living with dementia in England do not feel they are getting sufficient post-diagnostic support.