J
John W. Newman
Researcher at University of California, Davis
Publications - 215
Citations - 12737
John W. Newman is an academic researcher from University of California, Davis. The author has contributed to research in topics: Epoxide hydrolase 2 & Fatty acid. The author has an hindex of 51, co-authored 208 publications receiving 11164 citations. Previous affiliations of John W. Newman include West Health & University of California, Santa Cruz.
Papers
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Journal ArticleDOI
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice.
Gertrud U. Schuster,Jennifer M. Bratt,Xiaowen Jiang,Theresa L. Pedersen,Dmitry Grapov,Yuriko Adkins,Darshan S. Kelley,Darshan S. Kelley,John W. Newman,John W. Newman,Nicholas J. Kenyon,Charles B. Stephensen +11 more
TL;DR: The proinflammatory effects of DHA suggest that the adverse effects of individual fatty acid formulations should be thoroughly considered before any use as therapeutic agents in asthma.
Journal ArticleDOI
imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel
Dmitry Grapov,John W. Newman +1 more
TL;DR: This tool provides access to multiple comparisons with false discovery correction, hierarchical clustering, principal and independent component analyses, partial least squares regression and discriminant analysis, through an intuitive interface for creating high-quality two- and a three-dimensional visualizations.
Patent
Inhibitors for the Soluble Epoxide Hydrolase
TL;DR: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases as mentioned in this paper, which is useful in many applications.
Journal ArticleDOI
Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids
Gregory C. Shearer,Gregory C. Shearer,Kamil Borkowski,Susan L. Puumala,William S. Harris,Theresa L. Pedersen,John W. Newman +6 more
TL;DR: It is concluded that MetSyn is associated with a disruption of lipoprotein oxylipin patterns consistent with greater inflammatory stress, and the partial correction of these dysoxylipinemias by treatment with omega-3 fatty acids could explain some of their beneficial effects.
Journal ArticleDOI
The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects.
Philip Hallenborg,Rasmus K. Petersen,Irene Kouskoumvekaki,John W. Newman,Lise Madsen,Karsten Kristiansen +5 more
TL;DR: Recent data on pathways involved in ligand production as well as possible endogenous, adipogenic PPARγ agonists are reviewed.