J
John W. Newman
Researcher at University of California, Davis
Publications - 215
Citations - 12737
John W. Newman is an academic researcher from University of California, Davis. The author has contributed to research in topics: Epoxide hydrolase 2 & Fatty acid. The author has an hindex of 51, co-authored 208 publications receiving 11164 citations. Previous affiliations of John W. Newman include West Health & University of California, Santa Cruz.
Papers
More filters
Journal ArticleDOI
Cytochrome p450-dependent lipid metabolism in preovulatory follicles.
John W. Newman,Jeanette E. Stok,Justin D. Vidal,C. J. Corbin,Q. Huang,Bruce D. Hammock,Alan J Conley +6 more
TL;DR: Roles for CYP-dependent arachidonic acid metabolites and their modulatory function in vascular models suggest roles for these metabolites in follicular maturation, which may include regulation of estradiol biosynthesis and preovulatory remodeling of the follicular wall that should be fully explored in future studies.
Journal ArticleDOI
Proteinuria increases oxylipid concentrations in VLDL and HDL but not LDL particles in the rat.
John W. Newman,John W. Newman,George A. Kaysen,George A. Kaysen,Bruce D. Hammock,Gregory C. Shearer,Gregory C. Shearer +6 more
TL;DR: Nephrotic syndrome alters the lipop protein oxylipid composition independently of an increase in total lipoprotein levels, and these proteinuria-induced changes may be associated with the cardiovascular risk of lipop Protein oxidation.
Journal ArticleDOI
Habitual Physical Activity and Plasma Metabolomic Patterns Distinguish Individuals with Low vs. High Weight Loss during Controlled Energy Restriction
Brian D. Piccolo,Brian D. Piccolo,Nancy L. Keim,Nancy L. Keim,Oliver Fiehn,Sean H. Adams,Sean H. Adams,Marta D. Van Loan,Marta D. Van Loan,John W. Newman,John W. Newman +10 more
TL;DR: Overweight and obese individuals highly responsive to energy restriction had accelerated reductions in adiposity, likely supported in part by higher lipid mobilization and combustion.
Journal ArticleDOI
Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice
Even Fjære,Ulrike L. Aune,Kristin Røen,Alison H. Keenan,Tao Ma,Kamil Borkowski,David Møbjerg Kristensen,Guy Wayne Novotny,Thomas Mandrup-Poulsen,Brian D. Hudson,Graeme Milligan,Yannan Xi,John W. Newman,Fawaz G. Haj,Bjørn Liaset,Karsten Kristiansen,Lise Madsen,Lise Madsen +17 more
TL;DR: In this paper, the effect of the anti-inflammatory compound indomethacin on glucose-stimulated insulin secretion (GSIS) was measured in vivo and in vitro using MIN6 β-cells.
Journal ArticleDOI
Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study
Ye Sun,Hiromi W. L. Koh,Hyungwon Choi,Woon-Puay Koh,Jian-Min Yuan,John W. Newman,Jin Su,Jinling Fang,Choon Nam Ong,Rob M. van Dam,Rob M. van Dam +10 more
TL;DR: Circulating long-chain n-3 FAs and stearic acid were associated with a lower risk of acute myocardial infarction in this Chinese population, but the association between the oxylipin TXB2 and AMI requires further research.