J
Jonathan A. Fletcher
Researcher at Brigham and Women's Hospital
Publications - 426
Citations - 57627
Jonathan A. Fletcher is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: GiST & PDGFRA. The author has an hindex of 109, co-authored 413 publications receiving 53642 citations. Previous affiliations of Jonathan A. Fletcher include Albany Medical College & Oregon Health & Science University.
Papers
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Journal Article
DNA in situ hybridization as an adjunct in tumor diagnosis.
TL;DR: The ISH applications are categorized with respect to diagnostic capabilities, ease of use, and cost, including the advantages and limitations of enzymatic detection ("insituhistochemistry").
Journal ArticleDOI
Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53
Wen-Bin Ou,Minmin Lu,Grant Eilers,Hailong Li,Jiongyan Ding,Xuli Meng,Yuehong Wu,Quan He,Qing Sheng,Hai-Meng Zhou,Jonathan A. Fletcher +10 more
TL;DR: Results indicate that NF2 regulates the interaction of FAK–p53 and MDM2– p53, and highlight novel therapeutic opportunities in mesothelioma.
Book ChapterDOI
Molecular biology and cytogenetics of soft tissue sarcomas: relevance for targeted therapies.
Journal ArticleDOI
Skeletal and extraskeletal myxoid chondrosarcoma: related or distinct tumors?
TL;DR: Designation as "chordoid sarcoma of bone" would distinguish these cases from conventional skeletal myxoid chondrosarcoma, and it is difficult to describe such tumors, unambiguously, using the present nomenclature.