J
Jonathan A. Winston
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 51
Citations - 4343
Jonathan A. Winston is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Kidney disease & Renal function. The author has an hindex of 27, co-authored 50 publications receiving 4151 citations. Previous affiliations of Jonathan A. Winston include Cardiovascular Institute of the South.
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Journal ArticleDOI
Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America
Samir K. Gupta,Joseph A. Eustace,Jonathan A. Winston,Ivy I. Boydstun,Tejinder S. Ahuja,Rudolph A. Rodriguez,Karen T. Tashima,Michelle E. Roland,Nora Franceschini,Frank J. Palella,Jeffrey L. Lennox,Paul E. Klotman,Sharon Nachman,Stephen D. Hall,Lynda A. Szczech +14 more
TL;DR: This research presents a meta-analysis of the immune system’s response to Epstein-Barr virus, which has the potential to improve the quality of life of patients and reduce the likelihood of adverse events.
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A phase 1/2 clinical trial of enzyme replacement in fabry disease: pharmacokinetic, substrate clearance, and safety studies.
Christine M. Eng,Maryam Banikazemi,Ronald E. Gordon,Martin E. Goldman,Robert G. Phelps,Leona Kim,Alan Gass,Jonathan A. Winston,Steven Dikman,John T. Fallon,Scott E. Brodie,Charles B. Stacy,Davendra Mehta,Rosaleen Parsons,Karen I. Norton,Michael O'Callaghan,Robert J. Desnick +16 more
TL;DR: A single-center, open-label, dose-ranging study of r-halphaGalA treatment in 15 patients, each of whom received five infusions at one of five dose regimens provides the basis for a phase 3 trial of enzyme-replacement therapy for Fabry disease.
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The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection
Lynda A. Szczech,Samir K. Gupta,Ramez Habash,Antonio Guasch,Robert C. Kalayjian,Richard G. Appel,Timothy A. Fields,Laura P. Svetkey,Katherine H. Flanagan,Paul E. Klotman,Jonathan A. Winston +10 more
TL;DR: Among HIV-infected patients with renal disease other than HIVAN, viral suppression and the use of antiretroviral therapy are not associated with a beneficial effect on renal function; thus, additional therapeutic strategies may need to be utilized.
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Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection.
Jonathan A. Winston,Leslie A. Bruggeman,Michael W. Ross,Jeffrey M. Jacobson,Leora Ross,Vivette D. D'Agati,Paul E. Klotman,Mary E. Klotman +7 more
TL;DR: HIV-1–associated nephropathy is characterized morphologically by focal segmental glomerulosclerosis, tubular microcysts, interstitial fibrosis, and inflammation, and increasing evidence suggests it is due to HIV-1 infection.
Journal ArticleDOI
Renal Epithelium Is a Previously Unrecognized Site of HIV-1 Infection
Leslie A. Bruggeman,Michael W. Ross,Nozomu Tanji,Andrea Cara,Steven Dikman,Ronald E. Gordon,Godfrey C. Burns,Vivette D. D'Agati,Jonathan A. Winston,Mary E. Klotman,Paul E. Klotman +10 more
TL;DR: Investigation of whether HIV-1 directly infects renal parenchymal cells suggests that effectively targeting the kidney with antiretrovirals may be critical for patients who are seropositive with renal disease.