Jonathan L. Kirschman

TL;DR: A single RNA sensitive fluorescent labeling method is presented which allows us to label and visualize synthetic mRNA without significantly affecting function and can facilitate near-infrared imaging of mRNA localization in vivo and in ex-vivo tissue sections, which will facilitate mRNA trafficking studies in pre-clinical models.

TL;DR: MTRIP labeling of viral RNA during virus assembly has the potential to become a general methodology for the labeling and study of many important RNA viruses, and individual viral particles can be characterized at subdiffraction-limited resolution.

TL;DR: It is discovered that plasma membrane-bound respiratory syncytial virus G rapidly recycles from the membrane via clathrin-mediated endocytosis and assembly with genomic ribonucleoproteins and caveolae-associated vesicles prior to re-insertion into the plasma membrane.

TL;DR: This review highlights key studies involved in the development of strategies employed to increase protein expression and control the immunogenicity of synthetic mRNA.

TL;DR: In this article, the authors describe the design of elliptically bent Kirkpatrick-Baez mirrors developed and successfully used at the Advanced Light Source for submicron focusing, and demonstrate that with active mirror-temperature stabilization, a change of the surrounding temperature by more than 3K does not noticeably affect the mirror figure.