J
Jongmin Lee
Researcher at Konkuk University
Publications - 97
Citations - 2194
Jongmin Lee is an academic researcher from Konkuk University. The author has contributed to research in topics: Stroke & Prospective cohort study. The author has an hindex of 26, co-authored 97 publications receiving 1774 citations. Previous affiliations of Jongmin Lee include Chonnam National University.
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Journal ArticleDOI
NADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's disease.
Dong Hee Choi,Ana C. Cristóvão,Ana C. Cristóvão,Ana C. Cristóvão,Subhrangshu Guhathakurta,Subhrangshu Guhathakurta,Jongmin Lee,Tong H. Joh,M. Flint Beal,Yoon Seong Kim,Yoon Seong Kim,Yoon Seong Kim +11 more
TL;DR: Evidence is provided that dopaminergic neurons are equipped with the Nox1/Rac1 superoxide-generating system, and the impact of oxidative stress caused by this system on the pathogenesis and therapy in Parkinson's disease is emphasized.
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Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the GSK-3β/β-catenin pathway.
Hyo Sang Go,Ki Chan Kim,Ki Chan Kim,Chang Soon Choi,Se Jin Jeon,Kyung Ja Kwon,Seol-Heui Han,Jongmin Lee,Jae Hoon Cheong,Jong Hoon Ryu,Chong-Hyun Kim,Chong-Hyun Kim,Kwang Ho Ko,Chan Young Shin +13 more
TL;DR: It is suggested that an altered developmental process underlies the macrocephaly and abnormal brain structure observed in the autistic brain.
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Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection.
Kyoung Ja Kwon,Jung Nam Kim,Min Kyeong Kim,Jongmin Lee,Louis J. Ignarro,Louis J. Ignarro,Hee Jin Kim,Chan Young Shin,Seol-Heui Han +8 more
TL;DR: Melatonin potentiates the neuroprotective effect of RSV against oxidative injury, by enhancing HO‐1 induction through inhibiting ubiquitination‐dependent proteasome pathway, which may provide an effective means to treat neurodegenerative disorders.
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Characterization of White Matter Injury in a Rat Model of Chronic Cerebral Hypoperfusion
Bo-Ryoung Choi,Dong-Hee Kim,Dong Bin Back,Chung Hwan Kang,Won-Jin Moon,Jung-Soo Han,Dong-Hee Choi,Kyoung Ja Kwon,Chan Young Shin,Bo-Ram Kim,Jongmin Lee,Seol-Heui Han,Hahn Young Kim +12 more
TL;DR: White matter injury induced by chronic cerebral hypoperfusion can be characterized by disintegration of diverse white matter components, and cilostazol might be a therapeutic strategy against white matter disintegration in patients with vascular dementia.
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Subchronic treatment of donepezil rescues impaired social, hyperactive, and stereotypic behavior in valproic acid-induced animal model of autism.
Ji-Woon Kim,Hana Seung,Kyung Ja Kwon,Mee Jung Ko,Eun Joo Lee,Hyun Ah Oh,Chang Soon Choi,Ki Chan Kim,Edson Luck Gonzales,Jueng Soo You,Dong-Hee Choi,Jongmin Lee,Seol-Heui Han,Sung Min Yang,Jae Hoon Cheong,Chan Young Shin,Geon Ho Bahn +16 more
TL;DR: Evidence is provided that dysregulation of ACh system represented by the up-regulation of acetylcholinesterase (AChE) may serve as an effective pharmacological therapeutic target against autistic behaviors in VPA animal model of ASD, which should be subjected for further investigation to verify the clinical relevance.