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Jörg Vogel

Researcher at University of Würzburg

Publications -  244
Citations -  31250

Jörg Vogel is an academic researcher from University of Würzburg. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 89, co-authored 216 publications receiving 26988 citations. Previous affiliations of Jörg Vogel include Humboldt State University & Uppsala University.

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Evidence for an autonomous 5′ target recognition domain in an Hfq-associated small RNA

TL;DR: It is shown that the conserved 5′ end of RybB sRNA recognizes multiple mRNAs of Salmonella outer membrane proteins by ≥7-bp Watson–Crick pairing, and is sufficient to guide target mRNA degradation and maintain σE-dependent envelope homeostasis.
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Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA

TL;DR: The classic MicF sRNA is assigned to the growing class of Hfq‐associated regulators that use diverse mechanisms to impact multiple loci and targets lpxR at both the ribosome binding site and deep within the coding sequence.
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A rough guide to the non-coding RNA world of Salmonella.

TL;DR: In this article, a review of the non-coding RNA world of Salmonella is presented, which covers small RNAs (sRNAs) that act as post-transcriptional regulators of gene expression, novel Salmonellas cis-regulatory RNA elements that sense metabolite and metal ion concentrations (or temperature), and globally acting RNA-binding proteins such as CsrA or Hfq (inactivation of which cause drastic phenotypes and virulence defects).
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A small non-coding RNA of the invasion gene island (SPI-1) represses outer membrane protein synthesis from the Salmonella core genome.

TL;DR: The first regulatory RNA of an enterobacterial pathogenicity island is identified, and new roles for Hfq and HilD in SPI‐1 gene expression are found, and InvR represses the synthesis of the abundant OmpD porin encoded by the Salmonella core genome.
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Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon

TL;DR: The finding that expression of either MicA or RybB sRNA protects the cell from the loss of viability experienced when σE activity is inadequate illustrates the importance of the posttranscriptional repression arm of the response.