J
Jörg Vogel
Researcher at University of Würzburg
Publications - 244
Citations - 31250
Jörg Vogel is an academic researcher from University of Würzburg. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 89, co-authored 216 publications receiving 26988 citations. Previous affiliations of Jörg Vogel include Humboldt State University & Uppsala University.
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Journal ArticleDOI
Recognition of the small regulatory RNA RydC by the bacterial Hfq protein
Daniela Dimastrogiovanni,Kathrin S. Fröhlich,Katarzyna J Bandyra,Heather A Bruce,Susann Hohensee,Jörg Vogel,Ben F. Luisi +6 more
TL;DR: A model for a dynamic effector complex comprising Hfq, small RNA, and the cognate mRNA target is proposed and proposed, which involves a host of distributed interactions mediated by the natively unstructured termini of HfQ.
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Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation
Sudip Das,Claudia Lindemann,Bernadette C. Young,Julius Muller,Babett Österreich,Nicola Ternette,Ann-Cathrin Winkler,Kerstin Paprotka,Richard Reinhardt,Konrad U. Förstner,Elizabeth R. Allen,Amy Flaxman,Yuko Yamaguchi,Christine S. Rollier,Pauline M. van Diemen,Sebastian Blättner,Christian W. Remmele,Martina Selle,Marcus Dittrich,Tobias Müller,Jörg Vogel,Knut Ohlsen,Derrick W. Crook,Ruth C. Massey,Daniel J. Wilson,Thomas Rudel,David H. Wyllie,Martin Fraunholz +27 more
TL;DR: A spontaneously evolving, attenuated-cytotoxicity, nonhemolytic S. aureus phenotype, controlled by a pleiotropic transcriptional regulator/noncoding RNA virulence regulatory system, capable of causing S.aureus bloodstream infections is identified.
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In vivo expression and purification of aptamer-tagged small RNA regulators
TL;DR: It is demonstrated that the common sRNA-binding protein, Hfq, co-purifies with MS2-tagged sRNAs of Salmonella, and the presented affinity purification strategy may facilitate the isolation of in vivo assembled sRNA–protein complexes in a wide range of bacteria.
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New RNA-seq approaches for the study of bacterial pathogens
TL;DR: Dual RNA-seq analyzing pathogen and host simultaneously has revealed roles of noncoding RNAs during infection and enabled the correlation of bacterial gene activity with specific host responses.
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Lariat formation and a hydrolytic pathway in plant chloroplast group II intron splicing
Jörg Vogel,Thomas Börner +1 more
TL;DR: It is demonstrated that all but one of the barley chloroplast introns splice via the common pathway that produces a branched product, the first example of naturally occurring hydrolytic group II intron splicing in vivo.