J
José I. Borrell
Researcher at Ramon Llull University
Publications - 140
Citations - 2101
José I. Borrell is an academic researcher from Ramon Llull University. The author has contributed to research in topics: Malononitrile & Virtual screening. The author has an hindex of 22, co-authored 133 publications receiving 1932 citations. Previous affiliations of José I. Borrell include Rohm and Haas & University of Aberdeen.
Papers
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Journal ArticleDOI
Two-Photon Absorption in Tetraphenylporphycenes: Are Porphycenes Better Candidates than Porphyrins for Providing Optimal Optical Properties for Two-Photon Photodynamic Therapy?
Jacob Arnbjerg,Ana Jiménez-Banzo,Martin J. Paterson,Santi Nonell,José I. Borrell,Ove Christiansen,Peter R. Ogilby +6 more
TL;DR: This study establishes that, in comparison to porphyrins and other tetrapyrrolic macrocyclic systems, porphycenes exhibit many desirable attributes for use as sensitizers in two-photon initiated photodynamic therapy.
Journal ArticleDOI
Porphycenes: facts and prospects in photodynamic therapy of cancer.
Juan C. Stockert,Magdalena Cañete,Angeles Juarranz,Angeles Villanueva,Richard W. Horobin,José I. Borrell,Jordi Teixidó,Santi Nonell +7 more
TL;DR: Porphycene derivatives show higher absorption than porphyrins in the red spectral region, fast uptake and diverse subcellular localizations, and photophysical and photobiological properties of porphycenes make them excellent candidates as PSs, very useful for PDT of cancer and other biomedical applications.
Journal ArticleDOI
APIF: a new interaction fingerprint based on atom pairs and its application to virtual screening.
TL;DR: Binding mode analyses showed that the first conformations retrieved by interaction fingerprint scores had a more similar binding mode to the reference complex than those retrieved by the GoldScore function.
Journal ArticleDOI
A three-component synthesis of pyrido[2,3-d]pyrimidines
TL;DR: In this paper, a microwave-assisted one-pot cyclocondensation of α, β-unsaturated esters, amidine systems and malononitrile (or ethyl cyanoacetate) is described.
Journal ArticleDOI
Comparison of ligand-based and receptor-based virtual screening of HIV entry inhibitors for the CXCR4 and CCR5 receptors using 3D ligand shape matching and ligand-receptor docking.
Violeta I. Pérez-Nueno,David W. Ritchie,Obdulia Rabal,Rosalia Pascual,José I. Borrell,Jordi Teixidó +5 more
TL;DR: A detailed comparison of the performance of receptor-based and ligand-based virtual screening approaches to find CXCR4 and CCR5 antagonists that could potentially serve as HIV entry inhibitors is described.